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TaxTree of Organism Leishmania major
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EC NUMBER 
COMMENTARY 
-
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
preliminary BRENDA-supplied EC number
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(3R)-N-[(2S)-1-hydroxy-6-[(3R)-3-isocyanobutanamido]hexan-2-yl]-3-isocyanobutanamide biosynthesis
-
-
PWY-8320
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)
-
-
PWY-7726
(5Z)-dodecenoate biosynthesis I
-
-
PWY0-862
(5Z)-dodecenoate biosynthesis II
-
-
PWY-7858
(5Z)-icosenoate biosynthesis
-
-
PWY-5361
(9Z)-tricosene biosynthesis
-
-
PWY-7035
(aminomethyl)phosphonate degradation
-
-
PWY-7805
(R)-cysteate degradation
-
-
PWY-6642
(S)-lactate fermentation to propanoate, acetate and hydrogen
-
-
PWY-8086
(S)-propane-1,2-diol degradation
-
-
PWY-7013
(S)-reticuline biosynthesis I
-
-
PWY-3581
1,2-dichloroethane degradation
-
-
12DICHLORETHDEG-PWY
1,3-propanediol biosynthesis (engineered)
-
-
PWY-7385
1,5-anhydrofructose degradation
-
-
PWY-6992
1-butanol autotrophic biosynthesis (engineered)
-
-
PWY-6886
2'-deoxymugineic acid phytosiderophore biosynthesis
-
-
PWY-5912
2,3-dihydroxybenzoate biosynthesis
-
-
PWY-5901
2-arachidonoylglycerol biosynthesis
-
-
PWY-8052
2-methyl-branched fatty acid beta-oxidation
-
-
PWY-8181
2-oxoglutarate decarboxylation to succinyl-CoA
-
-
PWY-5084
2-oxoisovalerate decarboxylation to isobutanoyl-CoA
-
-
PWY-5046
24-epi-campesterol, fucosterol, and clionasterol biosynthesis (diatoms)
-
-
PWY-8238
3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent)
-
-
CHLOROPHYLL-SYN
3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)
-
-
PWY-7159
3-(4-hydroxyphenyl)pyruvate biosynthesis
-
-
PWY-5886
3-hydroxy-4-methyl-anthranilate biosynthesis I
-
-
PWY-7717
3-hydroxy-4-methyl-anthranilate biosynthesis II
-
-
PWY-7765
3-hydroxypropanoate cycle
-
-
PWY-5743
3-hydroxypropanoate/4-hydroxybutanate cycle
-
-
PWY-5789
3-methylbutanol biosynthesis (engineered)
-
-
PWY-6871
3-phosphoinositide biosynthesis
-
-
PWY-6352
3-phosphoinositide degradation
-
-
PWY-6368
4-aminobutanoate degradation V
-
-
PWY-5022
4-hydroxy-2-nonenal detoxification
-
-
PWY-7112
4-hydroxybenzoate biosynthesis I (eukaryotes)
-
-
PWY-5754
4-oxopentanoate degradation
-
-
PWY-7948
5-oxo-L-proline metabolism
-
-
PWY-7942
6-gingerol analog biosynthesis (engineered)
-
-
PWY-6920
8-amino-7-oxononanoate biosynthesis I
-
-
PWY-6519
8-amino-7-oxononanoate biosynthesis IV
-
-
PWY-8203
ABH and Lewis epitopes biosynthesis from type 1 precursor disaccharide
-
-
PWY-7832
ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide
-
-
PWY-7831
Ac/N-end rule pathway
-
-
PWY-7800
acetaldehyde biosynthesis I
-
-
PWY-6333
acetaldehyde biosynthesis II
-
-
PWY-6330
acetate and ATP formation from acetyl-CoA III
-
-
PWY-8328
acetate conversion to acetyl-CoA
-
-
PWY0-1313
acetone degradation I (to methylglyoxal)
-
-
PWY-5451
acetone degradation III (to propane-1,2-diol)
-
-
PWY-7466
acetylene degradation (anaerobic)
-
-
P161-PWY
acrylonitrile degradation I
-
-
PWY-7308
acyl carrier protein activation
-
-
PWY-6012-1
acyl carrier protein metabolism
-
-
PWY-6012
adenine and adenosine salvage I
-
-
P121-PWY
adenine and adenosine salvage III
-
-
PWY-6609
adenine and adenosine salvage V
-
-
PWY-6611
adenosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7227
adenosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7220
adenosine nucleotides degradation I
-
-
PWY-6596
adenosine nucleotides degradation II
-
-
SALVADEHYPOX-PWY
adenosine ribonucleotides de novo biosynthesis
-
-
PWY-7219
adlupulone and adhumulone biosynthesis
-
-
PWY-7857
aerobic respiration I (cytochrome c)
-
-
PWY-3781
aerobic respiration II (cytochrome c) (yeast)
-
-
PWY-7279
aerobic respiration III (alternative oxidase pathway)
-
-
PWY-4302
aldoxime degradation
-
-
P345-PWY
all-trans-farnesol biosynthesis
-
-
PWY-6859
alpha-linolenate metabolites biosynthesis
-
-
PWY-8398
alpha-tomatine degradation
-
-
PWY18C3-5
Amaryllidacea alkaloids biosynthesis
-
-
PWY-7826
ammonia oxidation II (anaerobic)
-
-
P303-PWY
anaerobic energy metabolism (invertebrates, cytosol)
-
-
PWY-7383
anaerobic energy metabolism (invertebrates, mitochondrial)
-
-
PWY-7384
anandamide biosynthesis I
-
-
PWY-8051
anandamide biosynthesis II
-
-
PWY-8053
anteiso-branched-chain fatty acid biosynthesis
-
-
PWY-8173
apratoxin A biosynthesis
-
-
PWY-8361
arachidonate biosynthesis I (6-desaturase, lower eukaryotes)
-
-
PWY-5353
arachidonate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7592
arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)
-
-
PWY-7601
arachidonate biosynthesis V (8-detaturase, mammals)
-
-
PWY-7725
arachidonate metabolites biosynthesis
-
-
PWY-8397
Arg/N-end rule pathway (eukaryotic)
-
-
PWY-7799
arsenate detoxification I
-
-
PWY-8264
arsenate detoxification III
-
-
PWY-8263
arsenate reduction (respiratory)
-
-
PWY-4601
arsenic detoxification (mammals)
-
-
PWY-4202
arsenic detoxification (plants)
-
-
PWY-8259
arsenic detoxification (yeast)
-
-
PWY-4621
arsenite to oxygen electron transfer
-
-
PWY-4521
arsenite to oxygen electron transfer (via azurin)
-
-
PWY-7429
arsonoacetate degradation
-
-
P482-PWY
ascorbate recycling (cytosolic)
-
-
PWY-6370
aspirin triggered resolvin D biosynthesis
-
-
PWY66-395
aspirin triggered resolvin E biosynthesis
-
-
PWY66-394
ATP biosynthesis
-
-
PWY-7980
atromentin biosynthesis
-
-
PWY-7518
bacterial bioluminescence
-
-
PWY-7723
baicalein degradation (hydrogen peroxide detoxification)
-
-
PWY-7214
baicalein metabolism
-
-
PWY-7212
beta-(1,4)-mannan degradation
-
-
PWY-7456
beta-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation
-
-
PWY-7586
beta-D-glucuronide and D-glucuronate degradation
-
-
PWY-7247
betanidin degradation
-
-
PWY-5461
Bifidobacterium shunt
-
-
P124-PWY
biosynthesis of Lewis epitopes (H. pylori)
-
-
PWY-7833
biotin-carboxyl carrier protein assembly
-
-
PWY0-1264
bisabolene biosynthesis (engineered)
-
-
PWY-7102
bupropion degradation
-
-
PWY66-241
butachlor degradation
-
-
PWY-7771
butanol and isobutanol biosynthesis (engineered)
-
-
PWY-7396
C20 prostanoid biosynthesis
-
-
PWY66-374
C25,25 CDP-archaeol biosynthesis
-
-
PWY-8365
C4 photosynthetic carbon assimilation cycle, NAD-ME type
-
-
PWY-7115
C4 photosynthetic carbon assimilation cycle, NADP-ME type
-
-
PWY-241
C4 photosynthetic carbon assimilation cycle, PEPCK type
-
-
PWY-7117
Calvin-Benson-Bassham cycle
-
-
CALVIN-PWY
camalexin biosynthesis
-
-
CAMALEXIN-SYN
canavanine degradation
-
-
PWY-31
cannabinoid biosynthesis
-
-
PWY-5140
CDP-6-deoxy-D-gulose biosynthesis
-
-
PWY-8139
CDP-diacylglycerol biosynthesis I
-
-
PWY-5667
CDP-diacylglycerol biosynthesis II
-
-
PWY0-1319
cell-surface glycoconjugate-linked phosphocholine biosynthesis
-
-
PWY-7886
cellulose degradation II (fungi)
-
-
PWY-6788
ceramide and sphingolipid recycling and degradation (yeast)
-
-
PWY-7119
ceramide de novo biosynthesis
-
-
PWY3DJ-12
chitin biosynthesis
-
-
PWY-6981
chitin deacetylation
-
-
PWY-7118
chitin degradation I (archaea)
-
-
PWY-6855
chitin degradation II (Vibrio)
-
-
PWY-6902
chitin degradation III (Serratia)
-
-
PWY-7822
chitin derivatives degradation
-
-
PWY-6906
chlorogenic acid degradation
-
-
PWY-6781
cholesterol biosynthesis (algae, late side-chain reductase)
-
-
PWY-8191
cholesterol biosynthesis (diatoms)
-
-
PWY-8239
cholesterol biosynthesis (plants, early side-chain reductase)
-
-
PWY18C3-1
cholesterol biosynthesis II (via 24,25-dihydrolanosterol)
-
-
PWY66-3
choline biosynthesis I
-
-
PWY-3385
choline biosynthesis III
-
-
PWY-3561
cis-geranyl-CoA degradation
-
-
PWY-6672
cis-vaccenate biosynthesis
CMP phosphorylation
-
-
PWY-7205
CMP-legionaminate biosynthesis I
-
-
PWY-6749
CO2 fixation into oxaloacetate (anaplerotic)
-
-
PWYQT-4429
coenzyme M biosynthesis II
-
-
PWY-6643
colanic acid building blocks biosynthesis
-
-
COLANSYN-PWY
colupulone and cohumulone biosynthesis
-
-
PWY-5133
complex N-linked glycan biosynthesis (plants)
-
-
PWY-7920
complex N-linked glycan biosynthesis (vertebrates)
-
-
PWY-7426
coumarin biosynthesis (via 2-coumarate)
-
-
PWY-5176
crepenynate biosynthesis
-
-
PWY-6013
curacin A biosynthesis
-
-
PWY-8358
cyanate degradation
cyclic electron flow
-
-
PWY-8270
cyclopropane fatty acid (CFA) biosynthesis
-
-
PWY0-541
cytosolic NADPH production (yeast)
-
-
PWY-7268
D-arabinose degradation V
-
-
PWY-8334
D-cycloserine biosynthesis
-
-
PWY-7274
D-galactose degradation I (Leloir pathway)
-
-
PWY-6317
D-galactose degradation IV
-
-
PWY-6693
D-galactose detoxification
-
-
PWY-3821
D-mannose degradation I
-
-
MANNCAT-PWY
D-mannose degradation II
-
-
PWY3O-1743
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
-
-
PWY-6351
D-myo-inositol-5-phosphate metabolism
-
-
PWY-6367
D-sorbitol biosynthesis I
-
-
PWY-5054
D-sorbitol degradation I
-
-
PWY-4101
degradation of aromatic, nitrogen containing compounds
-
-
detoxification of reactive carbonyls in chloroplasts
-
-
PWY-6786
di-homo-gamma-linolenate metabolites biosynthesis
-
-
PWY-8396
diacylglycerol and triacylglycerol biosynthesis
-
-
TRIGLSYN-PWY
diethylphosphate degradation
-
-
PWY-5491
dimethyl sulfide biosynthesis from methionine
-
-
PWY-7793
dissimilatory sulfate reduction I (to hydrogen sufide))
-
-
DISSULFRED-PWY
divinyl ether biosynthesis II
-
-
PWY-5409
docosahexaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-7053
docosahexaenoate biosynthesis III (6-desaturase, mammals)
-
-
PWY-7606
docosahexaenoate metabolites biosynthesis
-
-
PWY-8400
drosopterin and aurodrosopterin biosynthesis
-
-
PWY-7442
dTDP-beta-L-rhamnose biosynthesis
-
-
DTDPRHAMSYN-PWY
dTMP de novo biosynthesis (mitochondrial)
-
-
PWY66-385
dZTP biosynthesis
-
-
PWY-8289
enterobactin biosynthesis
Entner-Doudoroff pathway I
-
-
PWY-8004
Entner-Doudoroff pathway II (non-phosphorylative)
-
-
NPGLUCAT-PWY
Entner-Doudoroff pathway III (semi-phosphorylative)
-
-
PWY-2221
ergosterol biosynthesis I
-
-
PWY-6075
ergosterol biosynthesis II
-
-
PWY-7154
ergothioneine biosynthesis I (bacteria)
-
-
PWY-7255
erythro-tetrahydrobiopterin biosynthesis I
-
-
PWY-5663
Escherichia coli serotype O:127 O antigen biosynthesis
-
-
PWY-8231
Escherichia coli serotype O:86 O antigen biosynthesis
-
-
PWY-7290
ethanol degradation I
-
-
ETOH-ACETYLCOA-ANA-PWY
ethanol degradation II
-
-
PWY66-21
ethanol degradation III
-
-
PWY66-161
ethanol degradation IV
-
-
PWY66-162
ethanolamine utilization
-
-
PWY0-1477
ethene biosynthesis I (plants)
-
-
ETHYL-PWY
ethene biosynthesis III (microbes)
-
-
PWY-6854
ethene biosynthesis IV (engineered)
-
-
PWY-7126
ethene biosynthesis V (engineered)
-
-
PWY-7124
even iso-branched-chain fatty acid biosynthesis
-
-
PWY-8175
fatty acid biosynthesis initiation (type I)
-
-
PWY-5966-1
fatty acid elongation -- saturated
-
-
FASYN-ELONG-PWY
fatty acid salvage
-
-
PWY-7094
Fe(II) oxidation
-
-
PWY-6692
ferrichrome A biosynthesis
-
-
PWY-7571
firefly bioluminescence
-
-
PWY-7913
fluoroacetate and fluorothreonine biosynthesis
-
-
PWY-6644
fluoroacetate degradation
-
-
PWY-6646
folate polyglutamylation
folate transformations I
-
-
PWY-2201
folate transformations II (plants)
-
-
PWY-3841
folate transformations III (E. coli)
-
-
1CMET2-PWY
formaldehyde assimilation I (serine pathway)
-
-
PWY-1622
formaldehyde assimilation II (assimilatory RuMP Cycle)
-
-
PWY-1861
formaldehyde assimilation III (dihydroxyacetone cycle)
-
-
P185-PWY
formaldehyde oxidation I
-
-
RUMP-PWY
formaldehyde oxidation II (glutathione-dependent)
-
-
PWY-1801
formaldehyde oxidation VII (THF pathway)
-
-
PWY-7909
formate assimilation into 5,10-methylenetetrahydrofolate
-
-
PWY-1722
formate to nitrite electron transfer
-
-
PWY0-1585
fructose 2,6-bisphosphate biosynthesis
-
-
PWY66-423
gamma-linolenate biosynthesis II (animals)
-
-
PWY-6000
GDP-6-deoxy-D-talose biosynthesis
-
-
PWY-5738
GDP-alpha-D-glucose biosynthesis
-
-
PWY-5661
GDP-D-perosamine biosynthesis
-
-
PWY-5739
GDP-D-rhamnose biosynthesis
-
-
GDPRHAMSYN-PWY
GDP-L-colitose biosynthesis
-
-
PWY-5740
GDP-L-fucose biosynthesis I (from GDP-D-mannose)
-
-
PWY-66
GDP-L-fucose biosynthesis II (from L-fucose)
-
-
PWY-6
GDP-mannose biosynthesis
-
-
PWY-5659
GDP-mycosamine biosynthesis
-
-
PWY-7573
GDP-N-acetyl-alpha-D-perosamine biosynthesis
-
-
PWY-8225
GDP-N-formyl-alpha-D-perosamine biosynthesis
-
-
PWY2B4Q-2
gliotoxin biosynthesis
-
-
PWY-7533
gluconeogenesis I
-
-
GLUCONEO-PWY
gluconeogenesis II (Methanobacterium thermoautotrophicum)
-
-
PWY-6142
gluconeogenesis III
-
-
PWY66-399
glucose and glucose-1-phosphate degradation
-
-
GLUCOSE1PMETAB-PWY
glucose degradation (oxidative)
-
-
DHGLUCONATE-PYR-CAT-PWY
glucosinolate biosynthesis from dihomomethionine
-
-
PWYQT-4471
glucosinolate biosynthesis from hexahomomethionine
-
-
PWYQT-4475
glucosinolate biosynthesis from homomethionine
-
-
PWY-1187
glucosinolate biosynthesis from pentahomomethionine
-
-
PWYQT-4474
glucosinolate biosynthesis from phenylalanine
-
-
PWY-2821
glucosinolate biosynthesis from tetrahomomethionine
-
-
PWYQT-4473
glucosinolate biosynthesis from trihomomethionine
-
-
PWYQT-4472
glucosinolate biosynthesis from tryptophan
-
-
PWY-601
glucosinolate biosynthesis from tyrosine
-
-
PWY-7901
glucosylglycerol biosynthesis
-
-
PWY-7902
glutathione biosynthesis
-
-
GLUTATHIONESYN-PWY
glutathione-mediated detoxification I
-
-
PWY-4061
glutathione-mediated detoxification II
-
-
PWY-6842
glutathione-peroxide redox reactions
-
-
PWY-4081
glutathionylspermidine biosynthesis
-
-
PWY-4121
glycerol degradation I
-
-
PWY-4261
glycerol degradation to butanol
-
-
PWY-7003
glycerol-3-phosphate shuttle
-
-
PWY-6118
glycerol-3-phosphate to cytochrome bo oxidase electron transfer
-
-
PWY0-1561
glycerol-3-phosphate to fumarate electron transfer
-
-
PWY0-1582
glycerol-3-phosphate to hydrogen peroxide electron transport
-
-
PWY0-1591
glycerophosphodiester degradation
-
-
PWY-6952
glycine betaine degradation I
-
-
PWY-3661
glycine betaine degradation II (mammalian)
-
-
PWY-3661-1
glycine betaine degradation III
-
-
PWY-8325
glycine biosynthesis I
-
-
GLYSYN-PWY
glycine biosynthesis II
-
-
GLYCINE-SYN2-PWY
glycine cleavage
-
-
GLYCLEAV-PWY
glycogen biosynthesis I (from ADP-D-Glucose)
-
-
GLYCOGENSYNTH-PWY
glycogen biosynthesis III (from alpha-maltose 1-phosphate)
-
-
PWY-7900
glycogen degradation I
-
-
GLYCOCAT-PWY
glycogen degradation II
-
-
PWY-5941
glycolysis I (from glucose 6-phosphate)
-
-
GLYCOLYSIS
glycolysis II (from fructose 6-phosphate)
-
-
PWY-5484
glycolysis III (from glucose)
-
-
ANAGLYCOLYSIS-PWY
glycolysis IV
-
-
PWY-1042
glycolysis V (Pyrococcus)
-
-
P341-PWY
glyoxylate assimilation
-
-
PWY-5744
glyoxylate cycle
-
-
GLYOXYLATE-BYPASS
glyphosate degradation III
-
-
PWY-7807
gondoate biosynthesis (anaerobic)
-
-
PWY-7663
guanine and guanosine salvage I
-
-
PWY-6620
guanine and guanosine salvage II
-
-
PWY-6599
guanosine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7226
guanosine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7222
guanosine nucleotides degradation I
-
-
PWY-6607
guanosine nucleotides degradation II
-
-
PWY-6606
guanosine nucleotides degradation III
-
-
PWY-6608
guanosine ribonucleotides de novo biosynthesis
-
-
PWY-7221
H. pylori 26695 O-antigen biosynthesis
-
-
PWY2DNV-5
heme b biosynthesis I (aerobic)
-
-
HEME-BIOSYNTHESIS-II
heme b biosynthesis II (oxygen-independent)
-
-
HEMESYN2-PWY
heme b biosynthesis V (aerobic)
-
-
HEME-BIOSYNTHESIS-II-1
heme degradation I
-
-
PWY-5874
heterolactic fermentation
-
-
P122-PWY
histamine biosynthesis
-
-
PWY-6173
homocysteine and cysteine interconversion
-
-
PWY-801
homoglutathione biosynthesis
-
-
PWY-6840
hydrogen sulfide biosynthesis II (mammalian)
-
-
PWY66-426
hydrogen to fumarate electron transfer
-
-
PWY0-1576
hydroxylated fatty acid biosynthesis (plants)
-
-
PWY-6433
i antigen and I antigen biosynthesis
-
-
PWY-7837
icosapentaenoate biosynthesis I (lower eukaryotes)
-
-
PWY-6958
icosapentaenoate biosynthesis II (6-desaturase, mammals)
-
-
PWY-7049
icosapentaenoate biosynthesis III (8-desaturase, mammals)
-
-
PWY-7724
icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)
-
-
PWY-7602
icosapentaenoate metabolites biosynthesis
-
-
PWY-8399
incomplete reductive TCA cycle
-
-
P42-PWY
indole glucosinolate activation (intact plant cell)
-
-
PWYQT-4477
indole-3-acetate biosynthesis II
-
-
PWY-581
indole-3-acetate biosynthesis III (bacteria)
-
-
PWY-3161
indole-3-acetate biosynthesis IV (bacteria)
-
-
PWY-5025
indole-3-acetate biosynthesis VI (bacteria)
-
-
TRPIAACAT-PWY
inosine 5'-phosphate degradation
-
-
PWY-5695
inulin degradation
-
-
PWY-8314
isoprene biosynthesis II (engineered)
-
-
PWY-7391
jadomycin biosynthesis
-
-
PWY-6679
jasmonic acid biosynthesis
-
-
PWY-735
juniperonate biosynthesis
-
-
PWY-7619
justicidin B biosynthesis
-
-
PWY-6824
ketogenesis
-
-
PWY66-367
L-alanine biosynthesis II
-
-
ALANINE-SYN2-PWY
L-alanine degradation II (to D-lactate)
-
-
ALACAT2-PWY
L-alanine degradation III
-
-
ALANINE-DEG3-PWY
L-alanine degradation V (oxidative Stickland reaction)
-
-
PWY-8189
L-alanine degradation VI (reductive Stickland reaction)
-
-
PWY-8188
L-arabinose degradation II
-
-
PWY-5515
L-arginine biosynthesis I (via L-ornithine)
-
-
ARGSYN-PWY
L-arginine biosynthesis II (acetyl cycle)
-
-
ARGSYNBSUB-PWY
L-arginine biosynthesis IV (archaea)
-
-
PWY-7400
L-arginine degradation I (arginase pathway)
-
-
ARGASEDEG-PWY
L-arginine degradation VI (arginase 2 pathway)
-
-
ARG-PRO-PWY
L-arginine degradation VII (arginase 3 pathway)
-
-
ARG-GLU-PWY
L-arginine degradation X (arginine monooxygenase pathway)
-
-
ARGDEG-V-PWY
L-arginine degradation XIII (reductive Stickland reaction)
-
-
PWY-8187
L-arginine degradation XIV (oxidative Stickland reaction)
-
-
PWY-6344
L-ascorbate degradation II (bacterial, aerobic)
-
-
PWY-6961
L-ascorbate degradation III
-
-
PWY-6960
L-asparagine degradation III (mammalian)
-
-
ASPARAGINE-DEG1-PWY-1
L-aspartate biosynthesis
-
-
ASPARTATESYN-PWY
L-aspartate degradation I
-
-
ASPARTATE-DEG1-PWY
L-carnitine degradation II
-
-
PWY-3641
L-citrulline biosynthesis
-
-
CITRULBIO-PWY
L-citrulline degradation
-
-
CITRULLINE-DEG-PWY
L-cysteine biosynthesis I
-
-
CYSTSYN-PWY
L-cysteine biosynthesis III (from L-homocysteine)
-
-
HOMOCYSDEGR-PWY
L-cysteine biosynthesis VI (reverse transsulfuration)
-
-
PWY-I9
L-cysteine biosynthesis VII (from S-sulfo-L-cysteine)
-
-
PWY-7870
L-cysteine degradation III
-
-
PWY-5329
L-dopa and L-dopachrome biosynthesis
-
-
PWY-6481
L-glutamate degradation I
-
-
GLUTAMATE-DEG1-PWY
L-glutamate degradation II
-
-
GLUTDEG-PWY
L-glutamate degradation V (via hydroxyglutarate)
-
-
P162-PWY
L-glutamate degradation XI (reductive Stickland reaction)
-
-
PWY-8190
L-histidine degradation III
-
-
PWY-5030
L-histidine degradation V
-
-
PWY-5031
L-isoleucine biosynthesis V
-
-
PWY-5108
L-isoleucine degradation II
-
-
PWY-5078
L-lactaldehyde degradation (aerobic)
-
-
PWY0-1317
L-leucine degradation I
-
-
LEU-DEG2-PWY
L-leucine degradation III
-
-
PWY-5076
L-lysine biosynthesis I
-
-
DAPLYSINESYN-PWY
L-malate degradation II
-
-
PWY-7686
L-methionine biosynthesis I
-
-
HOMOSER-METSYN-PWY
L-methionine biosynthesis II
-
-
PWY-702
L-methionine degradation I (to L-homocysteine)
-
-
METHIONINE-DEG1-PWY
L-methionine degradation III
-
-
PWY-5082
L-Ndelta-acetylornithine biosynthesis
-
-
PWY-6922
L-phenylalanine biosynthesis I
-
-
PHESYN
L-phenylalanine degradation I (aerobic)
-
-
PHENYLALANINE-DEG1-PWY
L-phenylalanine degradation II (anaerobic)
-
-
ANAPHENOXI-PWY
L-phenylalanine degradation III
-
-
PWY-5079
L-phenylalanine degradation IV (mammalian, via side chain)
-
-
PWY-6318
L-phenylalanine degradation V
-
-
PWY-7158
L-phenylalanine degradation VI (reductive Stickland reaction)
-
-
PWY-8014
L-rhamnose degradation II
-
-
PWY-6713
L-selenocysteine biosynthesis I (bacteria)
-
-
PWY0-901
L-selenocysteine biosynthesis II (archaea and eukaryotes)
-
-
PWY-6281
L-serine biosynthesis I
-
-
SERSYN-PWY
L-threonine biosynthesis
-
-
HOMOSER-THRESYN-PWY
L-tryptophan degradation I (via anthranilate)
-
-
TRPCAT-PWY
L-tryptophan degradation IV (via indole-3-lactate)
-
-
TRPKYNCAT-PWY
L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
-
-
PWY-5651
L-tryptophan degradation V (side chain pathway)
-
-
PWY-3162
L-tryptophan degradation VIII (to tryptophol)
-
-
PWY-5081
L-tryptophan degradation XI (mammalian, via kynurenine)
-
-
PWY-6309
L-tryptophan degradation XIII (reductive Stickland reaction)
-
-
PWY-8017
L-tyrosine biosynthesis I
-
-
TYRSYN
L-tyrosine biosynthesis IV
-
-
PWY-6134
L-tyrosine degradation I
-
-
TYRFUMCAT-PWY
L-tyrosine degradation II
-
-
PWY-5151
L-tyrosine degradation III
-
-
PWY3O-4108
L-tyrosine degradation IV (to 4-methylphenol)
-
-
PWY-7514
L-tyrosine degradation V (reductive Stickland reaction)
-
-
PWY-8016
L-valine degradation II
-
-
PWY-5057
lactate biosynthesis (archaea)
-
-
PWY-5197
lacto-series glycosphingolipids biosynthesis
-
-
PWY-7839
lanosterol biosynthesis
-
-
PWY-6132
linamarin degradation
-
-
PWY-3121
linoleate metabolites biosynthesis
-
-
PWY-8395
linustatin bioactivation
-
-
PWY-7091
lipid A-core biosynthesis (E. coli K-12)
-
-
LIPA-CORESYN-PWY
lipid IVA biosynthesis (2,3-diamino-2,3-dideoxy-D-glucopyranose-containing)
-
-
PWY2B4Q-4
lipid IVA biosynthesis (E. coli)
-
-
NAGLIPASYN-PWY
lipid IVA biosynthesis (generic)
-
-
PWY-8283
lipid IVA biosynthesis (H. pylori)
-
-
PWYI-14
lipid IVA biosynthesis (P. gingivalis)
-
-
PWY-8245
lipid IVA biosynthesis (P. putida)
-
-
PWY-8073
lipid IVA biosynthesis (Vibrio cholerae serogroup O1 El Tor)
-
-
PWY2G6Z-2
lipoxin biosynthesis
-
-
PWY66-392
long chain fatty acid ester synthesis (engineered)
-
-
PWY-6873
lotaustralin degradation
-
-
PWY-6002
lupulone and humulone biosynthesis
-
-
PWY-5132
luteolin triglucuronide degradation
-
-
PWY-7445
malate/L-aspartate shuttle pathway
-
-
MALATE-ASPARTATE-SHUTTLE-PWY
mannitol biosynthesis
-
-
PWY-3881
mannitol cycle
-
-
PWY-6531
mannitol degradation II
-
-
PWY-3861
maresin biosynthesis
-
-
PWY-8356
matairesinol biosynthesis
-
-
PWY-5466
melatonin degradation I
-
-
PWY-6398
menaquinol-4 biosynthesis II
-
-
PWY-7998
Methanobacterium thermoautotrophicum biosynthetic metabolism
-
-
PWY-6146
methanol oxidation to formaldehyde IV
-
-
PWY-5506
methyl indole-3-acetate interconversion
-
-
PWY-6303
methyl phomopsenoate biosynthesis
-
-
PWY-7721
methylaspartate cycle
methylglyoxal degradation I
-
-
PWY-5386
methylglyoxal degradation III
-
-
PWY-5453
methylglyoxal degradation IV
-
-
PWY-5459
methylglyoxal degradation V
-
-
PWY-5458
methylglyoxal degradation VI
-
-
MGLDLCTANA-PWY
methylglyoxal degradation VIII
-
-
PWY-5386-1
methylsalicylate degradation
-
-
PWY18C3-24
mevalonate degradation
-
-
PWY-5074
mevalonate pathway I (eukaryotes and bacteria)
-
-
PWY-922
mevalonate pathway II (haloarchaea)
-
-
PWY-6174
mevalonate pathway III (Thermoplasma)
-
-
PWY-7524
mevalonate pathway IV (archaea)
-
-
PWY-8125
mitochondrial NADPH production (yeast)
-
-
PWY-7269
mixed acid fermentation
-
-
FERMENTATION-PWY
mucin core 1 and core 2 O-glycosylation
-
-
PWY-7433
mucin core 3 and core 4 O-glycosylation
-
-
PWY-7435
mycolate biosynthesis
-
-
PWYG-321
mycolyl-arabinogalactan-peptidoglycan complex biosynthesis
-
-
PWY-6397
N-3-oxalyl-L-2,3-diaminopropanoate biosynthesis
-
-
PWY-8071
N-acetylglucosamine degradation I
-
-
GLUAMCAT-PWY
NAD salvage (plants)
-
-
PWY-5381
NAD salvage pathway I (PNC VI cycle)
-
-
PYRIDNUCSAL-PWY
NAD salvage pathway III (to nicotinamide riboside)
-
-
NAD-BIOSYNTHESIS-II
NAD salvage pathway V (PNC V cycle)
-
-
PWY3O-4107
NAD(P)/NADPH interconversion
-
-
PWY-5083
NADH to cytochrome bd oxidase electron transfer I
-
-
PWY0-1334
NADH to cytochrome bd oxidase electron transfer II
-
-
PWY0-1568
NADH to cytochrome bo oxidase electron transfer I
-
-
PWY0-1335
NADH to cytochrome bo oxidase electron transfer II
-
-
PWY0-1567
NADH to fumarate electron transfer
-
-
PWY0-1336
NADPH to cytochrome c oxidase via plastocyanin
-
-
PWY-8271
neolinustatin bioactivation
-
-
PWY-7092
nicotine degradation IV
-
-
PWY66-201
nicotine degradation V
-
-
PWY66-221
nitrate reduction I (denitrification)
-
-
DENITRIFICATION-PWY
nitrate reduction IX (dissimilatory)
-
-
PWY0-1581
nitrate reduction VII (denitrification)
-
-
PWY-6748
nitrate reduction VIIIb (dissimilatory)
-
-
PWY0-1573
nitrate reduction X (dissimilatory, periplasmic)
-
-
PWY0-1584
nitric oxide biosynthesis II (mammals)
-
-
PWY-4983
nitrifier denitrification
-
-
PWY-7084
nitrite-dependent anaerobic methane oxidation
-
-
PWY-6523
nitrogen remobilization from senescing leaves
-
-
PWY-6549
nocardicin A biosynthesis
-
-
PWY-7797
nonaprenyl diphosphate biosynthesis I
-
-
PWY-5805
nonaprenyl diphosphate biosynthesis II
-
-
PWY-6520
noradrenaline and adrenaline degradation
-
-
PWY-6342
nucleoside and nucleotide degradation (archaea)
-
-
PWY-5532
O-antigen building blocks biosynthesis (E. coli)
-
-
OANTIGEN-PWY
o-diquinones biosynthesis
-
-
PWY-6752
octane oxidation
-
-
P221-PWY
octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)
-
-
PWY-7388
odd iso-branched-chain fatty acid biosynthesis
-
-
PWY-8174
oleandomycin activation/inactivation
-
-
PWY-6972
oleate biosynthesis II (animals and fungi)
-
-
PWY-5996
oleate biosynthesis III (cyanobacteria)
-
-
PWY-7587
oleate biosynthesis IV (anaerobic)
-
-
PWY-7664
ophthalmate biosynthesis
-
-
PWY-8043
palmitate biosynthesis I (type I fatty acid synthase)
-
-
PWY-5994
palmitate biosynthesis II (type II fatty acid synthase)
-
-
PWY-5971
palmitate biosynthesis III
-
-
PWY-8279
palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)
-
-
PWY-6282
palmitoleate biosynthesis IV (fungi and animals)
-
-
PWY3O-1801
palmitoyl ethanolamide biosynthesis
-
-
PWY-8055
partial TCA cycle (obligate autotrophs)
-
-
PWY-5913
pentachlorophenol degradation
-
-
PCPDEG-PWY
pentose phosphate pathway (non-oxidative branch) I
-
-
NONOXIPENT-PWY
pentose phosphate pathway (non-oxidative branch) II
-
-
PWY-8178
pentose phosphate pathway (oxidative branch) I
-
-
OXIDATIVEPENT-PWY
pentose phosphate pathway (partial)
-
-
P21-PWY
peptido-conjugates in tissue regeneration biosynthesis
-
-
PWY-8355
peptidoglycan recycling I
-
-
PWY0-1261
peptidoglycan recycling II
-
-
PWY-7883
petrobactin biosynthesis
-
-
PWY-6289
petroselinate biosynthesis
-
-
PWY-5367
phenylethanol biosynthesis
-
-
PWY-5751
pheomelanin biosynthesis
-
-
PWY-7917
phosphate acquisition
-
-
PWY-6348
phosphatidate biosynthesis (yeast)
-
-
PWY-7411
phosphatidate metabolism, as a signaling molecule
-
-
PWY-7039
phosphatidylcholine acyl editing
-
-
PWY-6803
phosphatidylcholine biosynthesis I
-
-
PWY3O-450
phosphatidylcholine biosynthesis II
-
-
PWY4FS-2
phosphatidylcholine biosynthesis V
-
-
PWY-6825
phosphatidylethanolamine biosynthesis II
-
-
PWY4FS-6
phosphatidylinositol biosynthesis I (bacteria)
-
-
PWY-6580
phospholipases
-
-
LIPASYN-PWY
phospholipid remodeling (phosphatidate, yeast)
-
-
PWY-7417
phospholipid remodeling (phosphatidylcholine, yeast)
-
-
PWY-7416
phospholipid remodeling (phosphatidylethanolamine, yeast)
-
-
PWY-7409
phosphopantothenate biosynthesis I
-
-
PANTO-PWY
photorespiration I
-
-
PWY-181
photorespiration II
-
-
PWY-8362
photorespiration III
-
-
PWY-8363
photosynthesis light reactions
-
-
PWY-101
photosynthetic 3-hydroxybutanoate biosynthesis (engineered)
-
-
PWY-7218
phytate degradation I
-
-
PWY-4702
phytol degradation
-
-
PWY66-389
phytosterol biosynthesis (plants)
-
-
PWY-2541
plasmalogen biosynthesis I (aerobic)
-
-
PWY-7782
plasmalogen degradation
-
-
PWY-7783
polyphosphate metabolism
-
-
PWY-8138
ppGpp metabolism
-
-
PPGPPMET-PWY
propanoyl CoA degradation I
-
-
PROPIONMET-PWY
protectin biosynthesis
-
-
PWY-8357
protein N-glycosylation initial phase (eukaryotic)
-
-
MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
protein N-glycosylation processing of mannoproteins (cis-Golgi, yeast)
-
-
PWY-8323
protein N-glycosylation processing of proteins targeted for retention in cellular organelles (cis-Golgi, yeast)
-
-
PWY-8322
protein N-glycosylation processing phase (plants and animals)
-
-
PWY-7919
protein S-nitrosylation and denitrosylation
-
-
PWY-7798
protein ubiquitination
-
-
PWY-7511
purine deoxyribonucleosides degradation I
-
-
PWY-7179
purine deoxyribonucleosides degradation II
-
-
PWY-7179-1
purine deoxyribonucleosides salvage
-
-
PWY-7224
purine nucleobases degradation I (anaerobic)
-
-
P164-PWY
purine nucleobases degradation II (anaerobic)
-
-
PWY-5497
purine ribonucleosides degradation
-
-
PWY0-1296
putrescine biosynthesis III
-
-
PWY-46
pyrimidine deoxyribonucleosides salvage
-
-
PWY-7199
pyrimidine deoxyribonucleotide phosphorylation
-
-
PWY-7197
pyrimidine deoxyribonucleotides biosynthesis from CTP
-
-
PWY-7210
pyrimidine deoxyribonucleotides de novo biosynthesis I
-
-
PWY-7184
pyrimidine deoxyribonucleotides de novo biosynthesis II
-
-
PWY-7187
pyrimidine deoxyribonucleotides de novo biosynthesis III
-
-
PWY-6545
pyrimidine deoxyribonucleotides de novo biosynthesis IV
-
-
PWY-7198
pyrimidine deoxyribonucleotides dephosphorylation
-
-
PWY-7206
pyrimidine nucleobases salvage II
-
-
PWY-7194
pyrimidine ribonucleosides salvage II
-
-
PWY-6556
pyrimidine ribonucleosides salvage III
-
-
PWY-7195
pyruvate decarboxylation to acetyl CoA I
-
-
PYRUVDEHYD-PWY
pyruvate fermentation to (R)-lactate
-
-
PWY-8274
pyruvate fermentation to (S)-lactate
-
-
PWY-5481
pyruvate fermentation to acetate VIII
-
-
PWY-5768
pyruvate fermentation to acetoin III
-
-
PWY3O-440
pyruvate fermentation to ethanol I
-
-
PWY-5480
pyruvate fermentation to ethanol II
-
-
PWY-5486
pyruvate fermentation to ethanol III
-
-
PWY-6587
pyruvate fermentation to isobutanol (engineered)
-
-
PWY-7111
pyruvate fermentation to propanoate I
-
-
P108-PWY
reactive oxygen species degradation
-
-
DETOX1-PWY-1
reductive acetyl coenzyme A pathway I (homoacetogenic bacteria)
-
-
CODH-PWY
reductive glycine pathway of autotrophic CO2 fixation
-
-
PWY-8303
reductive TCA cycle I
-
-
P23-PWY
reductive TCA cycle II
-
-
PWY-5392
resolvin D biosynthesis
-
-
PWY66-397
retinol biosynthesis
-
-
PWY-6857
ribose phosphorylation
-
-
RIBOKIN-PWY
rosmarinic acid biosynthesis I
-
-
PWY-5048
Rubisco shunt
-
-
PWY-5723
S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine degradation
-
-
PWY-8302
S-adenosyl-L-methionine biosynthesis
-
-
SAM-PWY
S-adenosyl-L-methionine salvage I
-
-
PWY-6151
S-adenosyl-L-methionine salvage II
-
-
PWY-5041
salidroside biosynthesis
-
-
PWY-6802
salinosporamide A biosynthesis
-
-
PWY-6627
Salmonella enterica serotype O:13 O antigen biosynthesis
-
-
PWY-8230
sciadonate biosynthesis
-
-
PWY-6598
sedoheptulose bisphosphate bypass
-
-
PWY0-1517
seleno-amino acid biosynthesis (plants)
-
-
PWY-6936
seleno-amino acid detoxification and volatilization I
-
-
PWY-6931
seleno-amino acid detoxification and volatilization III
-
-
PWY-6933
serotonin degradation
-
-
PWY-6313
sesamin biosynthesis
-
-
PWY-5469
sorgoleone biosynthesis
-
-
PWY-5987
spermidine biosynthesis I
-
-
BSUBPOLYAMSYN-PWY
spermidine biosynthesis III
-
-
PWY-6834
spermine biosynthesis
-
-
ARGSPECAT-PWY
sphingolipid biosynthesis (mammals)
-
-
PWY-7277
sphingolipid biosynthesis (plants)
-
-
PWY-5129
sphingolipid biosynthesis (yeast)
-
-
SPHINGOLIPID-SYN-PWY
sphingomyelin metabolism
-
-
PWY3DJ-11281
sporopollenin precursors biosynthesis
-
-
PWY-6733
stachyose degradation
-
-
PWY-6527
starch biosynthesis
-
-
PWY-622
starch degradation I
-
-
PWY-842
starch degradation III
-
-
PWY-6731
starch degradation V
-
-
PWY-6737
stearate biosynthesis I (animals)
-
-
PWY-5972
stearate biosynthesis II (bacteria and plants)
-
-
PWY-5989
stearate biosynthesis IV
-
-
PWY-8280
stellatic acid biosynthesis
-
-
PWY-7736
sterculate biosynthesis
-
-
PWY-4942
sterol:steryl ester interconversion (yeast)
-
-
PWY-7424
stigma estolide biosynthesis
-
-
PWY-6453
streptomycin biosynthesis
-
-
PWY-5940
streptorubin B biosynthesis
-
-
PWY1A0-6120
succinate to chytochrome c oxidase via cytochrome c6
-
-
PWY1YI0-2
succinate to cytochrome bd oxidase electron transfer
-
-
PWY0-1353
succinate to cytochrome bo oxidase electron transfer
-
-
PWY0-1329
succinate to cytochrome c oxidase via plastocyanin
-
-
PWY1YI0-3
succinate to plastoquinol oxidase
-
-
PWY1YI0-8
sucrose biosynthesis I (from photosynthesis)
-
-
SUCSYN-PWY
sucrose biosynthesis II
-
-
PWY-7238
sucrose biosynthesis III
-
-
PWY-7347
sucrose degradation I (sucrose phosphotransferase)
-
-
SUCUTIL-PWY
sucrose degradation II (sucrose synthase)
-
-
PWY-3801
sucrose degradation III (sucrose invertase)
-
-
PWY-621
sucrose degradation IV (sucrose phosphorylase)
-
-
PWY-5384
sucrose degradation V (sucrose alpha-glucosidase)
-
-
PWY66-373
sucrose degradation VII (sucrose 3-dehydrogenase)
-
-
SUCROSEUTIL2-PWY
sulfide oxidation IV (mitochondria)
-
-
PWY-7927
sulfite oxidation II
-
-
PWY-5279
sulfite oxidation III
-
-
PWY-5278
sulfolactate degradation III
-
-
PWY-6638
superoxide radicals degradation
-
-
DETOX1-PWY
superpathway of fermentation (Chlamydomonas reinhardtii)
-
-
PWY4LZ-257
superpathway of glucose and xylose degradation
-
-
PWY-6901
superpathway of glycolysis and the Entner-Doudoroff pathway
-
-
GLYCOLYSIS-E-D
superpathway of glyoxylate cycle and fatty acid degradation
-
-
PWY-561
superpathway of methylsalicylate metabolism
-
-
PWY18C3-25
superpathway of ornithine degradation
-
-
ORNDEG-PWY
superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli)
-
-
PWY0-166
superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis
-
-
PWY-7328
taurine biosynthesis III
-
-
PWY-8359
TCA cycle I (prokaryotic)
-
-
TCA
TCA cycle II (plants and fungi)
-
-
PWY-5690
TCA cycle III (animals)
-
-
PWY66-398
TCA cycle IV (2-oxoglutarate decarboxylase)
-
-
P105-PWY
TCA cycle V (2-oxoglutarate synthase)
-
-
PWY-6969
TCA cycle VI (Helicobacter)
-
-
REDCITCYC
TCA cycle VII (acetate-producers)
-
-
PWY-7254
TCA cycle VIII (Chlamydia)
-
-
TCA-1
terminal O-glycans residues modification (via type 2 precursor disaccharide)
-
-
PWY-7434
tetradecanoate biosynthesis (mitochondria)
-
-
PWY66-430
tetrahydrofolate biosynthesis I
-
-
PWY-6614
tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate
-
-
PWY-6613
tetrahydropteridine recycling
-
-
PWY-8099
thioredoxin pathway
-
-
THIOREDOX-PWY
thiosulfate disproportionation IV (rhodanese)
-
-
PWY-5350
threo-tetrahydrobiopterin biosynthesis
-
-
PWY-6983
trans, trans-farnesyl diphosphate biosynthesis
-
-
PWY-5123
traumatin and (Z)-3-hexen-1-yl acetate biosynthesis
-
-
PWY-5410
trehalose degradation I (low osmolarity)
-
-
TREDEGLOW-PWY
trehalose degradation II (cytosolic)
-
-
PWY0-1182
trehalose degradation IV
-
-
PWY-2722
trehalose degradation V
-
-
PWY-2723
triacylglycerol degradation
-
-
LIPAS-PWY
tRNA charging
-
-
TRNA-CHARGING-PWY
tRNA processing
-
-
PWY0-1479
tRNA splicing I
-
-
PWY-6689
trypanothione biosynthesis
-
-
TRYPANOSYN-PWY
tunicamycin biosynthesis
-
-
PWY-7821
type I lipoteichoic acid biosynthesis (S. aureus)
-
-
PWY-7817
type IV lipoteichoic acid biosynthesis (S. pneumoniae)
-
-
PWY-7818
UDP-alpha-D-galactofuranose biosynthesis
-
-
PWY-7622
UDP-alpha-D-galactose biosynthesis
-
-
PWY-7344
UDP-alpha-D-glucose biosynthesis
-
-
PWY-7343
UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)
-
-
PWY-4841
UDP-N-acetyl-D-galactosamine biosynthesis II
-
-
PWY-5514
UDP-N-acetyl-D-galactosamine biosynthesis III
-
-
PWY-8013
UDP-N-acetyl-D-glucosamine biosynthesis I
-
-
UDPNAGSYN-PWY
UDP-N-acetyl-D-glucosamine biosynthesis II
-
-
UDPNACETYLGALSYN-PWY
UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)
-
-
PWY-6387
UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
-
-
PWY-6386
UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)
-
-
PWY-7953
ultra-long-chain fatty acid biosynthesis
-
-
PWY-8041
UMP biosynthesis I
-
-
PWY-5686
UMP biosynthesis II
-
-
PWY-7790
UMP biosynthesis III
-
-
PWY-7791
urea cycle
urea degradation II
-
-
PWY-5704
UTP and CTP de novo biosynthesis
-
-
PWY-7176
UTP and CTP dephosphorylation I
-
-
PWY-7185
UTP and CTP dephosphorylation II
-
-
PWY-7177
valproate beta-oxidation
-
-
PWY-8182
vancomycin resistance I
-
-
PWY-6454
vanillin biosynthesis I
-
-
PWY-5665
very long chain fatty acid biosynthesis I
-
-
PWY-5080
very long chain fatty acid biosynthesis II
-
-
PWY-7036
vitamin K-epoxide cycle
wogonin metabolism
-
-
PWY-7213
xanthine and xanthosine salvage
-
-
SALVPURINE2-PWY
xanthommatin biosynthesis
-
-
PWY-8249
xyloglucan degradation II (exoglucanase)
-
-
PWY-6807
zymosterol biosynthesis
-
-
PWY-6074
cis-vaccenate biosynthesis
-
-
PWY-5973
cyanate degradation
-
-
CYANCAT-PWY
enterobactin biosynthesis
-
-
ENTBACSYN-PWY
folate polyglutamylation
-
-
PWY-2161
methylaspartate cycle
-
-
PWY-6728
urea cycle
-
-
PWY-4984
vitamin K-epoxide cycle
-
-
PWY-7999
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
209985, 286583, 390842, 390843, 392255, 392293, 484952, 484953, 484955, 484957, 485389, 485404, 641527, 645558, 647655, 647656, 657286, 657430, 661573, 661698, 661751, 663550, 666287, 666531, 667783, 669790, 670193, 670321, 670825, 670848, 670874, 670984, 671029, 671092, 671156, 672294, 672523, 672817, 673544, 674795, 675351, 675870, 675874, 676964, 678377, 680716, 680747, 681817, 681820, 682957, 683549, 683897, 684118, 685400, 685820, 686025, 688896, 690754, 692049, 692329, 692687, 693074, 694466, 697682, 697817, 698047, 698983, 699388, 700281, 701497, 703220, 703221, 705599, 705607, 708298, 708611, 709867, 711796, 711946, 712697, 712978, 714055, 714377, 714875, 715934, 718253, 720404, 720841, 720877, 721238, 721301, 724335, 724484, 725417, 725475, 726385, 726820, 728427, 728592, 729176, 729177, 729840, 733157, 737349, 740019, 742445, 744843, 748827, 753525, 753822, 759709, 761069, 761074, 761864
-
-
-
645569, 647654, 652571, 659297, 661294, 661612, 668091, 671860, 672817, 674571, 681984, 697408, 704833, 754807, 754978, 755218, 758831, 759751
SwissProt
-
654109, 655580, 675869, 681458, 685676, 688890, 689793, 693074, 704709, 712979, 717812, 720406, 722975, 730548, 733157, 736617, 737371, 737392, 737715, 739404, 739821, 740879, 743300, 743328, 743626, 744529, 745655, 745735, 746914, 747205, 748426, 750234, 750734, 751333, 754074, 754973, 755511, 756324, 756376, 756532, 757688, 759641, 761918, 761959, 762083, 762206, 762463, 764262, 764535, 764625, 764989, 765008, 765412, 765428
D3G6S4, E9ADF9, E9AEQ8, E9AFX2, O15922, O97193, P22045, Q01782, Q27683, Q4FX34, Q4Q0M0, Q4Q124, Q4Q1I2, Q4Q1I3, Q4Q1I9, Q4Q3K2, Q4Q5S8, Q4Q6Y2, Q4Q869, Q4Q9F9, Q4QB75, Q4QC75, Q4QCF1, Q4QCW3, Q4QDQ6, Q4QDW1, Q4QE27, Q4QE75, Q4QEB3, Q4QEZ7, Q4QFI1, Q4QFJ7, Q4QFY1, Q4QHM7, Q4QHU7, Q4QIH2, Q4QIH7, Q4QIU7, Q6UQ31, Q6WRI4, Q711P7
UniProt
bifunctional dihydrofolate reductase-thymidylate synthase, cf. EC 2.1.1.45
UniProt
bifunctional enzyme dihydrofolate reductase-thymidylate synthase
-
-
comparison of enzyme in different strains. Considerable variability in amount and proteolytical activity of enzyme among the strains. Attenuated LV561/AV line shows low amount and low enzymatic activity. Strains L119, Neal defective in lipophosphoglycan exhibit enzyme overexpression
-
-
constituvie expression of enzyme in both extracellular and intracellular stages
-
-
cytoplasmic dynein, heavy chain 1; organism contains two dynein-2 isoforms
SwissProt
isozyme PGKB; gene PGKB codes for the cytosolic isoform of the enzyme
UniProt
isozyme PGKC; gene PGKC codes for the glycosomal isoform of the enzyme
UniProt
Leishmania major has four genes occurring in tandem arrays, with at least three of them encoding active bifunctional enzymes
UniProt
single copy gene, 3 isozymes A, B, and C of the type II enzyme
SwissProt
strain MHOM/IL/81, isolated from footpad lesions of infected BALB/c mice
-
-
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
-
637511, 645569, 659297, 661573, 666288, 705607, 714875, 718253, 720877, 721301, 744529, 744843, 750734, 755748, 759709, 761074
expressed to a higher extent in promastigotes than in amastigotes
E9AFE7, P08148, P50312, Q27683, Q4Q116 and Q4QI03, Q4Q1I9, Q4QEZ7, Q7K9G0, Q8I8A4, Q8WR00, Q8WR01, Q8WSZ0, Q9GPZ4
-
31229, 390843, 393550, 393551, 637511, 641527, 645569, 647656, 659297, 661573, 662902, 666288, 666531, 670193, 676964, 680716, 681817, 688890, 692329, 692687, 705607, 718253, 720877, 725475, 730121, 733044, 738183, 744843, 748827, 750734, 754978, 755218, 755748, 759709
expressed to a higher extent in promastigotes than in amastigotes. Induction increases over time and the strongest mRNA induction is observed at day 7, suggesting that invertase expression is highly expressed by promastigotes at stationary phase
additional information
-
high enzyme activity during the exponential growth phase of the parasite, but low during stationary phase
additional information
the phosphatase is predominantly expressed and secreted by promastigotes via the exosome route. Ectopic expression of LmPRL-1 in Leishmania major leads to an increased number of parasites in host macrophages
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LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY
GeneOntology No.
LITERATURE
SOURCE
additional information
-
645569, 656105, 661751, 662802, 670193, 681817, 700281, 704833, 705599, 712978, 725417, 729840, 730121, 738183, 762083
-
by immunofluorescence and electron microscopy studies it is shown that sterol methenyltransferase is primarily associated to the endoplasmic reticulum. In addition to this localisation, the protein is incorporated into translucent vesicles presumably of the endocytic pathway
mainly located in the endoplasmic reticulum
metacyclic promastigote exosomes contain the highest, and logarithmic exosomes have the lowest abundance of total major surface protease GP63. Among the major surface protease classes, major surface protease C class has the greatest variety of isoforms, but is least abundant in all exosomes. All major surface protease classes are present at higher levels in exosomes released from stationary or metacyclic promastigotes than logarithmic promastigotes
-
the host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole. The enzyme is released from the parasite surface following phagocytosis and is redistributed to the endoplasmic reticulum of macrophages
-
-
-
-
-
localisation shown in Saccharomyces cerevisiae via GFP-fusion proteins
the enzyme contains a mitochondrial targeting sequence with the first 40 amino acid residues at the N-terminus, the enzyme is imported into mitochondrial vesicles in vitro, the enzyme is processed after entry into mitochondria
the host cell secretory pathway mediates the export of Leishmania virulence factors out of the parasitophorous vacuole
additional information
-
DHCH1 is not localized in the mitochondrion or other vesicular compartments
-
additional information
-
enolase is found both in the secretome and in association with the surface of Leishmania spp.
-
additional information
in procyclic cells, LAP-A is equally distributed throughout the cytoplasm, yet upon starvation, it relocalizes in particles that concentrate in the perinuclear region. Effect of nutritional starvation on LAP-A subcellular localization
-
additional information
-
SHMT-L in an organelle that has hallmarks of the parasite mitochondrion
-
additional information
subcellular localization of LmPRL-1 in Leishmania major promastigotes depends on its C-terminal farnesylation
-
additional information
-
the enzyme does not localize to glycosomes and has no peroxisome-targeting signal
-
LINKS TO OTHER DATABASES (specific for Leishmania major)
SILVA: 16S/18S rRNA, 23S/28S rRNA
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Release 2023.1 (January 2023)
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