Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 3.5.1.89 - N-acetylglucosaminylphosphatidylinositol deacetylase

for references in articles please use BRENDA:EC3.5.1.89

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

Involved in the second step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes. The enzyme appears to be composed of a single subunit (PIG-L in mammalian cells and GPI12 in yeast). In some species, the long-chain sn-1-acyl group of the phosphatidyl group is replaced by a long-chain alkyl or alk-1-enyl group.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
glcnac-pi de-n-acetylase, pig-l, gpi12, tbgpi12, cagpi12, pig-l protein, denac, glcnac-pi-de-n-acetylase, n-acetylglucosaminylphosphatidylinositol deacetylase, n-acetylglucosaminyl phosphatidylinositol de-n-acetylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate
show the reaction diagram