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Information on EC 2.3.1.42 - glycerone-phosphate O-acyltransferase
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EC Tree
2.3.1.42 glycerone-phosphate O-acyltransferaseIUBMB Comments
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.
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Word Map
- 2.3.1.42
- peroxisomal
- plasmalogens
- zellweger
-
chondrodysplasia
-
rhizomelic
- punctata
- glycerolipids
-
phytanic
- alkyl-dhap
- hemochromatosis
- adrenoleukodystrophy
-
stippling
-
cerebro-hepato-renal
-
lignoceric
- refsum
- medicine
- analysis
The enzyme appears in viruses and cellular organisms
Synonyms
gnpat, dihydroxyacetone phosphate acyltransferase, dhap-at, dhapat, dihydroxyacetonephosphate acyltransferase, dhap acyltransferase, dihydroxyacetone-phosphate acyltransferase, lmdat, glyceronephosphate o-acyltransferase, dap-at, 
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
acyltransferase, dihydroxyacetone phosphate
-
-
-
-
DAP-AT
DHAP acyltransferase
DHAP-AT
DHAPAT
dihydroxyacetone phosphate acyltransferase
dihydroxyacetonephosphate acyltransferase
LmDAT
male sterility protein
TtFARAT
dihydroxyacetone phosphate acyltransferase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate
-
-
-
-
acyl-CoA + glycerone phosphate = CoA + acylglycerone phosphate
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
Acyl group transfer
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
acyl-CoA:glycerone-phosphate O-acyltransferase
A membrane protein. Uses CoA derivatives of palmitate, stearate and oleate, with highest activity on palmitoyl-CoA.
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CAS REGISTRY NUMBER
COMMENTARY
37257-19-5
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
arachidonoyl-CoA + dihydroxyacetone phosphate
CoA + arachidonoyldihydroxyacetone phosphate
arachidonoyl-CoA + glycerone phosphate
CoA + arachidonoylglycerone phosphate
-
less than 10% activity compared to palmitoyl-CoA
-
-
?
cis-9-hexadecenoyl-CoA + dihydroxyacetone phosphate
CoA + cis-9-hexadecenoyldihydroxyacetone phosphate
dihydroxyacetone phosphate + arachidoyl-CoA
1-arachidoyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + lauroyl-CoA
1-lauroyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + linoleoyl-CoA
1-linoleoyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + myristoyl-CoA
1-myristoyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + oleoyl-CoA
1-oleoyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + palmitoleoyl-CoA
1-palmitoleoyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + stearoyl-CoA
1-stearoyl-glycerone phosphate + CoA
-
-
-
-
?
elaidoyl-CoA + dihydroxyacetone phosphate
CoA + elaidoyldihydroxyacetone phosphate
-
poor substrate, mitochondrial enzyme
-
-
?
heptadecanoyl-CoA + dihydroxyacetone phosphate
CoA + heptadecanoyldihydroxyacetone phosphate
-
-
-
-
?
lauroyl-CoA + glycerone phosphate
CoA + lauroylglycerone phosphate
-
less than 10% activity compared to palmitoyl-CoA
-
-
?
lignoceroyl-CoA + dihydroxyacetone phosphate
CoA + lignoceroyldihydroxyacetone phosphate
-
poor substrate
-
-
?
linoleoyl-CoA + glycerone phosphate
CoA + linoleoylglycerone phosphate
-
about 25% activity compared to palmitoyl-CoA
-
-
?
myristoyl-CoA + glycerone phosphate
CoA + myristoylglycerone phosphate
-
about 60% activity compared to palmitoyl-CoA
-
-
?
nonadecanoyl-CoA + dihydroxyacetone phosphate
CoA + nonadecanoyldihydroxyacetone phosphate
-
poor substrate
-
-
?
nonanoyl-CoA + dihydroxyacetone phosphate
CoA + nonanoyldihydroxyacetone phosphate
-
poor substrate
-
-
?
octadecenoyl-CoA + dihydroxyacetone phosphate
CoA + heptadecenoyldihydroxyacetone phosphate
-
-
-
?
oleoyl-CoA + glycerone phosphate
CoA + oleoylglycerone phosphate
-
about 35% activity compared to palmitoyl-CoA
-
-
?
palmitoleoyl-CoA + glycerone phosphate
CoA + palmitoleoylglycerone phosphate
-
about 60% activity compared to palmitoyl-CoA
-
-
?
palmitoyl-CoA + glycerone phosphate
CoA + palmitoylglycerone phosphate
-
100% activity. Palmitoyl-CoA is the preferred acyl-CoA donor
-
-
?
pentadecanoyl-CoA + dihydroxyacetone phosphate
CoA + pentadecanoyldihydroxyacetone phosphate
-
-
-
-
?
stearoyl-CoA + glycerone phosphate
CoA + 1-stearoyl-glycerone phosphate
-
-
-
?
stearoyl-CoA + glycerone phosphate
CoA + stearoylglycerone phosphate
-
about 20% activity compared to palmitoyl-CoA
-
-
?
tetradecanoyl-CoA + dihydroxyacetone phosphate
CoA + tetradecanoyldihydroxyacetone phosphate
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
r
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
i.e. glycerone phosphate, saturated acyl-CoAs preferred over unsaturated
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
i.e. glycerone phosphate, saturated acyl-CoAs preferred over unsaturated
i.e. acylglycerone phosphate
r
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
ir
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
no acyl-acceptor is glycerol 3-phosphate
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
ir
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
ir
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
no acyl-donors are C4-C10-acyl-CoAs
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
i.e. acylglycerone phosphate
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
?
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
-
-
ir
acyl-CoA + dihydroxyacetone phosphate
CoA + acyldihydroxyacetone phosphate
-
no acyl-donors are C4-C10-acyl-CoAs
i.e. acylglycerone phosphate
?
acyl-CoA + glycerone phosphate
CoA + 1-acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + 1-acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
enzyme is essential for biosynthesis of plasmalogens and nonetherlipids, the peroxisomal isozymes does not contribute to nonetherlipid biosynthesis
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
enzyme is essential for biosynthesis of plasmalogens and nonetherlipids, the peroxisomal isozymes does not contribute to nonetherlipid biosynthesis
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
-
-
-
?
acyl-CoA + glycerone phosphate
CoA + acylglycerone phosphate
enzyme is involved in biosynthesis of plasmalogens, regulating enzyme
-
-
?
arachidonoyl-CoA + dihydroxyacetone phosphate
CoA + arachidonoyldihydroxyacetone phosphate
-
i.e. eicosatetraenoyl-CoA, poor substrate
-
-
?
arachidonoyl-CoA + dihydroxyacetone phosphate
CoA + arachidonoyldihydroxyacetone phosphate
-
i.e. eicosatetraenoyl-CoA, poor substrate
-
-
r
cis-9-hexadecenoyl-CoA + dihydroxyacetone phosphate
CoA + cis-9-hexadecenoyldihydroxyacetone phosphate
-
-
-
-
?
cis-9-hexadecenoyl-CoA + dihydroxyacetone phosphate
CoA + cis-9-hexadecenoyldihydroxyacetone phosphate
-
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
the enzyme performs the initial and obligatory step in the biosynthesis of ether lipids in most organisms that synthesize alkylglycerolipids and is important for rapid growth and survival at high cell density and essential for virulence, overview, lack of DAT causes a major alteration in parasite division during the logarithmic phase of growth, an accelerated cell death during stationary phase, and loss of virulence in mice
-
-
?
dihydroxyacetone phosphate + acyl-CoA
1-acyl-glycerone phosphate + CoA
-
-
-
-
?
dihydroxyacetone phosphate + palmitoyl-CoA
palmitoyl-glycerone phosphate + CoA
-
palmitoyl-CoA is the preferred acyl-CoA substrate
-
-
?
dihydroxyacetone phosphate + palmitoyl-CoA
palmitoyl-glycerone phosphate + CoA
-
-
-
-
?
dodecanoyl-CoA + dihydroxyacetone phosphate
CoA + dodecanoyldihydroxyacetone phosphate
-
-
-
-
?
dodecanoyl-CoA + dihydroxyacetone phosphate
CoA + dodecanoyldihydroxyacetone phosphate
-
-
-
-
?
dodecanoyl-CoA + dihydroxyacetone phosphate
CoA + dodecanoyldihydroxyacetone phosphate
-
i.e. lauroyl-CoA, poor substrate
-
-
?
linoleoyl-CoA + dihydroxyacetone phosphate
CoA + linoleoyldihydroxyacetone phosphate
-
-
-
-
r
linoleoyl-CoA + dihydroxyacetone phosphate
CoA + linoleoyldihydroxyacetone phosphate
-
poor substrate, mitochondrial enzyme
-
-
?
oleoyl-CoA + dihydroxyacetone phosphate
CoA + oleoyldihydroxyacetone phosphate
-
poor substrate
-
-
?
oleoyl-CoA + dihydroxyacetone phosphate
CoA + oleoyldihydroxyacetone phosphate
-
poor substrate
-
-
r
oleoyl-CoA + dihydroxyacetone phosphate
CoA + oleoyldihydroxyacetone phosphate
-
mitochondrial enzyme
-
-
?
oleoyl-CoA + dihydroxyacetone phosphate
CoA + oleoyldihydroxyacetone phosphate
-
-
-
-
?
oleoyl-CoA + dihydroxyacetone phosphate
CoA + oleoyldihydroxyacetone phosphate
-
poor substrate
-
-
?
oleoyl-CoA + glycerone phosphate
CoA + 1-oleoyl-glycerone phosphate
-
-
-
?
oleoyl-CoA + glycerone phosphate
CoA + 1-oleoyl-glycerone phosphate
-
-
-
?
palmitoleyl-CoA + glycerone phosphate
CoA + 1-palmitoleyl-glycerone phosphate
-
-
-
?
palmitoleyl-CoA + glycerone phosphate
CoA + 1-palmitoleyl-glycerone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
best substrate
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
best substrate
-
r
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
not palmitoylcarnitine
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
r
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
r
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
initiates glycerolipid, especially ether-linked glycerolipid, biosynthesis in higher eukaryotes
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
best substrate
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
recombinant in Saccharomyces cerevisiae cells
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
recombinant in Saccharomyces cerevisiae cells
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
best substrate
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
mitochondrial enzyme
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
peroxisomal enzyme involved in ether lipid biosynthesis
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
?
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
-
-
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
no precursor for glycerol ether lipids
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
obligate precursor in ether lipids biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
reaction in phosphatidic acid biosynthesis
-
ir
palmitoyl-CoA + dihydroxyacetone phosphate
CoA + monopalmitoyldihydroxyacetone phosphate
-
initiates glycerolipid, especially ether-linked glycerolipid, biosynthesis in higher eukaryotes
-
-
?
palmitoyl-CoA + glycerone phosphate
CoA + 1-palmitoyl-glycerone phosphate
palmitoyl-CoA is the preferred substrate
-
-
?
palmitoyl-CoA + glycerone phosphate
CoA + 1-palmitoyl-glycerone phosphate
palmitoyl-CoA is the preferred substrate
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
ir
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
acylation at 35% the rate of palmitoyl-CoA
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
ir
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
ir
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
ir
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
?
stearoyl-CoA + dihydroxyacetone phosphate
CoA + stearoyldihydroxyacetone phosphate
-
-
-
-
ir
tetradecanoyl-CoA + dihydroxyacetone phosphate
CoA + tetradecanoyldihydroxyacetone phosphate
-
i.e. myristoyl-CoA
-
-
?
tetradecanoyl-CoA + dihydroxyacetone phosphate
CoA + tetradecanoyldihydroxyacetone phosphate
-
i.e. myristoyl-CoA
-
-
?
tetradecanoyl-CoA + dihydroxyacetone phosphate
CoA + tetradecanoyldihydroxyacetone phosphate
-
i.e. myristoyl-CoA
-
-
?
tetradecanoyl-CoA + dihydroxyacetone phosphate
CoA + tetradecanoyldihydroxyacetone phosphate
-
i.e. myristoyl-CoA
-
-
?
additional information
?
-
-
enzyme activity is reduced with disorders: neonatal adrenoleukodystrophy, infantile Refsum disease, and hyperpipecolic acidemia
-
-
?
additional information
?
-
-
enzyme amount is reduced by 90% in Zellweger syndrome
-
-
?
additional information
?
-
-
enzyme amount is reduced by 90% in Zellweger syndrome
-
-
?
additional information
?
-
-
patients affected with rhizomelic chondrodysplasia punctata show reduced enzyme activity due to a defect in peroxisomal targeting
-
-
?
additional information
?
-
-
patients affected with rhizomelic chondrodysplasia punctata show reduced enzyme activity due to a defect in peroxisomal targeting
-
-
?
additional information
?
-
-
the enzyme is involved in the first step of plasmalogen biosynthesis, overview
-
-
?
additional information
?
-
-
Gat1 and Gat2 proteins are glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferases
-
-
?
additional information
?
-
the bifunctional enzyme preferentially displays dihydroxyacetone phosphate acyltransferase activity, substrate specificity, overview
-
-
?
additional information
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the bifunctional enzyme preferentially displays dihydroxyacetone phosphate acyltransferase activity, substrate specificity, overview
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?
additional information
?
-
the bifunctional enzyme preferentially displays dihydroxyacetone phosphate acyltransferase activity, substrate specificity, overview
-
-
?
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