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Literature summary for 2.3.1.42 extracted from

  • Piano, V.; Nenci, S.; Magnani, F.; Aliverti, A.; Mattevi, A.
    Recombinant human dihydroxyacetonephosphate acyl-transferase characterization as an integral monotopic membrane protein (2016), Biochem. Biophys. Res. Commun., 481, 51-58 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293E cells and Pichia pastoris KM71H MutS strain Homo sapiens

Protein Variants

Protein Variants Comment Organism
DHAPATDELTA135 the mutant enzyme is completely inactive Homo sapiens

General Stability

General Stability Organism
the enzyme activity and stability is dependent on alkyl-dihydroxyacetone phosphate synthase presence Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisomal membrane inner side of the peroxisomal membrane Homo sapiens 5778
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + glycerone phosphate Homo sapiens
-
CoA + acylglycerone phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens O15228
-
-

Purification (Commentary)

Purification (Comment) Organism
Ni-Sepharose resin column chromatography, His-Trap column chromatography and Superdex S200 gel filtration Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + glycerone phosphate
-
Homo sapiens CoA + acylglycerone phosphate
-
?

Subunits

Subunits Comment Organism
? x * 70000, recombinant enzyme, SDS-PAGE Homo sapiens
? x * 109000, recombinant enzyme fused to enhanced green fluorescent protein, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
DHAPAT
-
Homo sapiens
dihydroxyacetone phosphate acyl-transferase
-
Homo sapiens