Information on EC 3.2.1.4 - cellulase

for references in articles please use BRENDA:EC3.2.1.4
Word Map on EC 3.2.1.4
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:


The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

EC NUMBER
COMMENTARY hide
3.2.1.4
-
RECOMMENDED NAME
GeneOntology No.
cellulase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
hydrolysis
-
-
hydrolysis of O-glycosyl bond
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
cellulose degradation II (fungi)
-
-
cellulose degradation
-
-
Starch and sucrose metabolism
-
-
Metabolic pathways
-
-
SYSTEMATIC NAME
IUBMB Comments
4-beta-D-glucan 4-glucanohydrolase
Will also hydrolyse 1,4-linkages in beta-D-glucans also containing 1,3-linkages.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-54-8
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
Actinomyces sp. 40 Korean Native Goat 40
-
UniProt
Manually annotated by BRENDA team
-
A0A0F7TAS1
UniProt
Manually annotated by BRENDA team
aff. tenuissima, GenBank Accession: HQ630970
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
aff. phaeospermum, GenBank Accession: HQ630967; aff. sacchari, GenBank Accession: HQ630961
-
-
Manually annotated by BRENDA team
i.e. Aspergillus fischeri
UniProt
Manually annotated by BRENDA team
i.e. Aspergillus fischeri
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
IFO31125
-
-
Manually annotated by BRENDA team
cmc-1
-
-
Manually annotated by BRENDA team
isolated from rice bran
-
-
Manually annotated by BRENDA team
aff. fumigatus, GenBank Accession: HQ631021
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
aff. pullans, GenBank Accession: HQ631013
-
-
Manually annotated by BRENDA team
Bacillus cellulyticus K-12
K-12
-
-
Manually annotated by BRENDA team
KSM-N257
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
CTP-09
-
-
Manually annotated by BRENDA team
isolated from a cellulose-degrading enrichment culture initiated from compost samples
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
N-4
-
-
Manually annotated by BRENDA team
N-4 (NK1)
-
-
Manually annotated by BRENDA team
Bacillus sp. (in: Bacteria) No. 1139
No. 1139
-
-
Manually annotated by BRENDA team
BME-15
-
-
Manually annotated by BRENDA team
CK-2
-
-
Manually annotated by BRENDA team
DR
UniProt
Manually annotated by BRENDA team
isolated from the longtime-thermal compost containing rich cellulose materials in a factory of Zhengzhou in China, gene celI15
UniProt
Manually annotated by BRENDA team
JA18
-
-
Manually annotated by BRENDA team
isolated from a metagenomic library of a long-term dry thermophilic methanogenic digester community; isolated from a thermophilic methanogenic digester community
UniProt
Manually annotated by BRENDA team
isoform BC-EG70a
UniProt
Manually annotated by BRENDA team
Bellamya chinensis laeta UM-2014
isoform BC-EG70a
UniProt
Manually annotated by BRENDA team
GenBank Accession: HQ631009
-
-
Manually annotated by BRENDA team
acidophilic fungus, CGMCC 2500, gene bgl7A
UniProt
Manually annotated by BRENDA team
-
Q9STD9
Uniprot
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
anaerobic fungal isolate, is purified from bovine rumen
-
-
Manually annotated by BRENDA team
strain NIAB 442 and its deoxyglucose- and streptomycin-resistant mutant 51 Smr
-
-
Manually annotated by BRENDA team
strain NIAB 442 and its deoxyglucose- and streptomycin-resistant mutant 51 Smr
-
-
Manually annotated by BRENDA team
CDBB 531 strain
SwissProt
Manually annotated by BRENDA team
CDBB 531 strain
SwissProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
aff. gramineum, GenBank Accession: HQ630973
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
GenBank Accession: HQ630978
-
-
Manually annotated by BRENDA team
-
A0A0P0E6S3
UniProt
Manually annotated by BRENDA team
aff. cladosporioides, GenBank Accession: HQ630971
-
-
Manually annotated by BRENDA team
-
A0ZT16
UniProt
Manually annotated by BRENDA team
aff. bassiana, GenBank Accession: HQ630968
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
isolated from a sample of a circumneutral geothermal pool at 94 C
UniProt
Manually annotated by BRENDA team
bifunctional endo-1,4-beta-mannanase/endoglucanase, EC 3.2.1.78/EC 3.2.1.4, respectively
UniProt
Manually annotated by BRENDA team
bifunctional endo-1,4-beta-mannanase/endoglucanase, EC 3.2.1.78/EC 3.2.1.4, respectively
UniProt
Manually annotated by BRENDA team
GenBank Accession: HQ631008
-
-
Manually annotated by BRENDA team
aff. nigrum, GenBank Accession: HQ630972
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
aff. salmonis, GenBank Accession: HQ630990; aff. spinifera, GenBank Accession: HQ631027
-
-
Manually annotated by BRENDA team
-
A7HLZ2
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
isolated from a cellulose-degrading enrichment culture initiated from compost samples
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
i.e. Polyporus tulipiferae
-
-
Manually annotated by BRENDA team
isolated from lime-applied garbage dumps
-
-
Manually annotated by BRENDA team
isolated from lime-applied garbage dumps
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
Lenzites trabea
-
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
bifunctional CMCase and chitosanase, reactions of EC 3.2.1.4 and EC 3.2.16, respectively
UniProt
Manually annotated by BRENDA team
bifunctional CMCase and chitosanase, reactions of EC 3.2.1.4 and EC 3.2.16, respectively
UniProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
Cavara, pathogenic strain T-1 (Ken53-33) and nonpathogenic strain O(THU3*1), strain C-3(N87), strain N-1(H373)
-
-
Manually annotated by BRENDA team
isolated from the marine sponge Dendrilla nigra
-
-
Manually annotated by BRENDA team
isolated from the marine sponge Dendrilla nigra
-
-
Manually annotated by BRENDA team
Japanese purple sea urchin
-
-
Manually annotated by BRENDA team
aff. bolleyi, GenBank Accession: HQ630981
-
-
Manually annotated by BRENDA team
GenBank Accession: HQ630974
-
-
Manually annotated by BRENDA team
NRRL 26519
-
-
Manually annotated by BRENDA team
NRRL 26519
-
-
Manually annotated by BRENDA team
aff. oryzae, GenBank Accession: HQ630982
-
-
Manually annotated by BRENDA team
-
MG570051
GenBank
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
IBT 20888
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
aff. glomerata, GenBank Accession: HQ630999; aff. herbarum, GenBank Accession: HQ630963
-
-
Manually annotated by BRENDA team
Phytomonas davidi
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
presence of two independent endogenous and symbiotic cellulolytic systems in flagellate-harboring termites
-
-
Manually annotated by BRENDA team
Y-20
-
-
Manually annotated by BRENDA team
F-40
SwissProt
Manually annotated by BRENDA team
aff. lignivora, GenBank Accession: HQ630984
-
-
Manually annotated by BRENDA team
Sporotrichum pulverulentum
Stachybotrys atra
-
-
-
Manually annotated by BRENDA team
NBRC 31817
UniProt
Manually annotated by BRENDA team
MTCC 1764
-
-
Manually annotated by BRENDA team
1326
-
-
Manually annotated by BRENDA team
CMCase 1 and 2
-
-
Manually annotated by BRENDA team
A2
-
-
Manually annotated by BRENDA team
contains two different types of CMCases type I and II
-
-
Manually annotated by BRENDA team
M23
-
-
Manually annotated by BRENDA team
member of glycoside hydrolase family 12
UniProt
Manually annotated by BRENDA team
putative; MT4 strain
UniProt
Manually annotated by BRENDA team
BCC18080
Uniprot
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Cel6A
-
-
Manually annotated by BRENDA team
endoglucanase E-4 precursor; Cel9A
SwissProt
Manually annotated by BRENDA team
DSM 27729
-
-
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
gene egl3
-
-
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
QM 9414, mutant strain
-
-
Manually annotated by BRENDA team
sandfly, Phlebotomus papatasi, infected
-
-
Manually annotated by BRENDA team
from rumen of Bos mutus, Rucel5B
UniProt
Manually annotated by BRENDA team
-
C7FFK1
UniProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
metabolism
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2 cellobiose
cellotetraose + H2O
show the reaction diagram
2',4'-dinitrophenyl-beta-D-cellobiose + H2O
?
show the reaction diagram
-
-
-
-
?
2,3-di-O-methylated cellulase + H2O
?
show the reaction diagram
-
2,3-di-O-methylated cellulase, having a trace amount of unsubstituted glucose units is hydrolyzed. Only the linkages between glucose units and 2,3-di-O-methylated units are cleaved. No hydrolysis of 2,3-di-O-methylcellulose, having every structural unit of them regioselectively substituted
-
-
?
2,4-dinitrophenyl beta-D-cellobioside + H2O
?
show the reaction diagram
4''',6'''-O-benzylidene 2-chloro-4-nitrophenyl-beta-cellotrioside + H2O
4'',6''-O-benzylidene beta-cellobioside + 2-chloro-4-nitrophenyl beta-D-glucoside
show the reaction diagram
4-methylumbelliferyl beta-cellotrioside + H2O
?
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl beta-D-cellobioside + H2O
?
show the reaction diagram
4-methylumbelliferyl beta-D-lactoside + H2O
4-methylumbelliferone + D-lactose
show the reaction diagram
4-methylumbelliferyl cellobioside + H2O
4-methylumbelliferone + cellobiose
show the reaction diagram
-
-
-
?
4-methylumbelliferyl cellobioside + H2O
?
show the reaction diagram
4-methylumbelliferyl-beta-D-lactoside + H2O
4-methylumbelliferone + D-lactose
show the reaction diagram
4-nitrophenyl 4,6-O-(3-oxobutylidene)-beta-D-cellopentaoside + H2O
4,6-O-(3-oxobutylidene)-beta-D-cellotriose + 4-nitrophenyl-beta-D-cellobioside
show the reaction diagram
4-nitrophenyl beta-D-cellobioside + H2O
4-nitrophenol + cellobiose
show the reaction diagram
-
0.16% of the activity with carboxymethyl cellulose
-
-
?
4-nitrophenyl beta-D-cellobioside + H2O
?
show the reaction diagram
C7FFK1
7.7% of the activity with carboxymethyl cellulose
-
-
?
4-nitrophenyl beta-D-glucopyranoside + H2O
4-nitrophenol + beta-D-glucose
show the reaction diagram
33.2% of the activtiy with carboxymethyl cellulose
-
-
?
4-nitrophenyl beta-D-glucopyranoside + H2O
4-nitrophenol + D-glucopyranose
show the reaction diagram
4-nitrophenyl beta-D-glucopyranoside + H2O
4-nitrophenol + D-glucose
show the reaction diagram
4-nitrophenyl beta-D-glucoside + H2O
4-nitrophenol + beta-D-glucose
show the reaction diagram
4-nitrophenyl beta-D-glucoside + H2O
4-nitrophenol + D-glucose
show the reaction diagram
33.2% of the activity with carboxymethyl cellulose
-
-
?
4-nitrophenyl cellobioside + H2O
4-nitrophenol + cellobiose
show the reaction diagram
4-nitrophenyl cellobioside + H2O
?
show the reaction diagram
-
-
-
?
4-nitrophenyl cellopentaoside + H2O
4-nitrophenol + cellopentaose
show the reaction diagram
-
-
-
-
?
4-nitrophenyl cellotetraoside + H2O
4-nitrophenol + cellotetraose
show the reaction diagram
-
-
-
-
?
4-nitrophenyl cellotrioside + H2O
4-nitrophenol + cellotriose
show the reaction diagram
-
-
-
-
?
4-nitrophenyl D-cellobioside + H2O
4-nitrophenol + cellobiose
show the reaction diagram
-
-
-
?
4-nitrophenyl D-cellobioside + H2O
4-nitrophenol + D-cellobiose
show the reaction diagram
F4YTG7
-
-
-
?
acid swollen cellulose + H2O
cellobiose + cellotriose
show the reaction diagram
endoglucanase with exohydrolytic activity
-
-
?
acid-swollen cellulose + H2O
?
show the reaction diagram
alpha-cellulose + H2O
?
show the reaction diagram
-
activity of the catalytic module EG1-CM is 58% of the activity with endoglucanase 1
-
-
?
alpha-chitin + H2O
?
show the reaction diagram
-
due to the binding, it seems chitin would be an inhibitor of Cel6B, Cel9A and Cel48A, but not of Cel6A and Cel5A
-
-
?
amorphic Solca Floc cellulose + H2O
?
show the reaction diagram
amorphous cellulose + H2O
?
show the reaction diagram
-
-
-
?
arabinan + H2O
?
show the reaction diagram
avicel + H2O
?
show the reaction diagram
avicel + H2O
cellobiose + ?
show the reaction diagram
avicel + H2O
cellobiose + cellotriose
show the reaction diagram
cellooligosaccharides production from Avicel is detected only when 0.00185 mkat of Xf818his are employed, and not when 16.67 nkat are used. Endoglucanase with exohydrolytic activity
-
-
?
avicel + H2O
cellobiose + glucose
show the reaction diagram
-
the main product is cellobiose together with a small amount of glucose, endoglucanase 35
-
-
?
avicel + H2O
D-glucose
show the reaction diagram
-
-
-
-
?
avicel + H2O
D-glucose + ?
show the reaction diagram
avicel + H3O
?
show the reaction diagram
azurine-labelled hydroxyethylcellulose + H2O
?
show the reaction diagram
bacterial microcrystalline cellulose + H2O
?
show the reaction diagram
bacterial microcrystalline cellulose + H2O
cellotetraose
show the reaction diagram
-
weak activity
83% cellotetraose + 11% cellotriose + 4% cellobiose
-
?
bacterial micropcrystalline cellulose + H2O
?
show the reaction diagram
-
-
-
-
?
bagasse + H2O
?
show the reaction diagram
-
steam-exploded bagasse
-
-
?
ball-milled cellulose + H2O
?
show the reaction diagram
-
-
-
-
?
barley 1,3-1,4-beta glucan + H2O
?
show the reaction diagram
-
-
-
-
?
barley beta-D-glucan + H2O
?
show the reaction diagram
barley beta-glucan + H2O
?
show the reaction diagram
barley glucan + H2O
?
show the reaction diagram
beechwood xylan + H2O
?
show the reaction diagram
beta-1,4-D-glucan + H2O
?
show the reaction diagram
V9PD44
-
-
-
?
beta-D-glucan + H2O
?
show the reaction diagram
-
-
-
-
?
beta-glucan + H2O
?
show the reaction diagram
beta-glucan + H2O
cellotriose + ?
show the reaction diagram
-
-
-
?
birchwood xylan + H2O
?
show the reaction diagram
carboxymethycellulose + H2O
?
show the reaction diagram
carboxymethyl cellulose + H2O
6 D-glucose
show the reaction diagram
F4YTG7
-
-
-
?
carboxymethyl cellulose + H2O
?
show the reaction diagram
carboxymethyl cellulose + H2O
cellobiose + ?
show the reaction diagram
carboxymethyl cellulose + H2O
cellobiose + cellotriose + ?
show the reaction diagram
carboxymethyl cellulose + H2O
cellotriose + cellobiose + D-glucose
show the reaction diagram
-
enzyme hydrolyzes internal beta-1,4 glycosidic bonds within lichenan as well as carboxymethyl cellulose to release oligosaccharides and glucose
major products
-
?
carboxymethyl cellulose + H2O
D-glucose
show the reaction diagram
carboxymethyl cellulose + H2O
D-glucose + ?
show the reaction diagram
carboxymethyl cellulose + H2O
D-glucose + cellobiose + cellooligosaccharide
show the reaction diagram
carboxymethyl cellulose + H2O
glucose + cellobiose + short oligomers
show the reaction diagram
carboxymethyl-cellulose + H2O
?
show the reaction diagram
<