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Information on EC 1.14.11.3 - pyrimidine-deoxynucleoside 2'-dioxygenase

for references in articles please use BRENDA:EC1.14.11.3

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IUBMB Comments

Requires Fe(II) and ascorbate. Also acts on thymidine. cf. EC 1.14.11.10, pyrimidine-deoxynucleoside 1′-dioxygenase.

The enzyme appears in viruses and cellular organisms

Synonyms
pyrimidine deoxyribonucleoside 2'-hydroxylase, deoxyuridine 2'-hydroxylase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2'-deoxyuridine + 2-oxoglutarate + O2 = uridine + succinate + CO2
show the reaction diagram
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