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cyanobacterial UDP-Glc PPase
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glucose 1-phosphate uridylyltransferase
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glucose-1-phosphate urididyltransferase
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glucose-1-phosphate uridyltransferase
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glucose-1-phosphate uridylyltransferase
plastid UDP-glucose pyrophosphorylase
sugar-1-phosphate nucleotidylyltransferase
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UDP glucose pyrophosphorylase
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UDP-Glc pyrophosphorylase
UDP-glucose pyrophosphorylase
UDP-glucose pyrophosphorylase 1
UDP-glucose pyrophosphorylase isoenzyme UGP5
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UDP-glucose pyrophosphorylase UGP1
Q94B70
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UDP-glucose pyrophosphorylase UGP2
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UDP-glucose pyrophosphorylase UGP3
Q94B70
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UDPG phosphorylase
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UDPglucose pyrophosphorylase
uridine 5'-diphosphoglucose pyrophosphorylase
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uridine diphosphate-D-glucose pyrophosphorylase
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uridine diphosphate-glucose pyrophosphorylase
uridine diphosphoglucose pyrophosphorylase
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uridine-diphosphate glucose pyrophosphorylase
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uridylyltransferase, glucose 1-phosphate
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UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase
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UTP:alpha-D-glucose uridylyltransferase
UTP:glucose-1-phosphate uridylyltransferase
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All3274
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ExoN
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GalU
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gfugp
MN788154
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Glc-1-P UTase
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glucose-1-phosphate uridylyltransferase
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glucose-1-phosphate uridylyltransferase
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plastid UDP-glucose pyrophosphorylase
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plastid UDP-glucose pyrophosphorylase
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ST0452
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ST0452
bifunctional enzyme exhibiting sugar-1-phosphate nucleotidylyltransferase and amino-sugar-1-phosphate acetyltransferase activities
TaGalU
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UDP-Glc pyrophosphorylase
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UDP-Glc pyrophosphorylase
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UDP-GlcPPase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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-
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
MN788154
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UDP-glucose pyrophosphorylase
MN788154
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase
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UDP-glucose pyrophosphorylase 1
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UDP-glucose pyrophosphorylase 1
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UDPG pyrophosphorylase
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UDPG-pyrophosphorylase
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UDPG-pyrophosphorylase
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UDPglucose pyrophosphorylase
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UDPglucose pyrophosphorylase
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UDPglucose pyrophosphorylase
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UGP
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UGP1
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UGP3
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UgpA
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UGPase
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UGPase1
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uridine diphosphate-glucose pyrophosphorylase
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uridine diphosphate-glucose pyrophosphorylase
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UTP:alpha-D-glucose uridylyltransferase
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UTP:alpha-D-glucose uridylyltransferase
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VldB
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
mechanism
Acetabularia sp.
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
sequential ordered bi bi reaction mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
sequential ordered bi bi reaction mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
sequential ordered bi bi reaction mechanism
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
Trp333 and Arg391 are essential for activity, while His266, Arg389, Arg422, Arg 445, and Trp218 are not
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
ordered bi-bi mechanism. The molecular geometry at position 4 of glucose is responsible for substrate specificity. The gamma-phosphate group of UTP is essential for binding and for induction of the open conformation, which then allows entry of glucose 1-phosphate
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
ordered sequential Bi Bi mechanism, overview. Pyrimidine bases may approach the base binding site, but they cannot form the tight interactions observed in the HpUGPase/UDP-Glc complex. Thymine binding would be hindered by its extra methyl group, and cytosine could not make specific hydrogen bonds
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
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ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-glucose
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13.7% of the activity with UTP
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r
CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-alpha-D-glucose
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-galactose
UTP + alpha-D-galactose 1-phosphate
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-mannose
UTP + D-mannose 1-phosphate
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
farnesyl triphosphate + UDP-glucose
farnesyl-tetraphosphouridine + alpha-D-glucose + diphosphate
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-
-
-
?
geranyl triphosphate + UDP-glucose
geranyl-tetraphosphouridine + alpha-D-glucose + diphosphate
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-
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
isopentenyl triphosphate + UDP-glucose
isopentenyl-tetraphosphouridine + alpha-D-glucose + diphosphate
-
-
-
-
?
methylenebisphosphonate + UDP-glucose
uridine 5'-(beta,gamma-methylenetriphosphate) + alpha-D-glucose + diphosphate
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-
-
-
?
monothiodiphosphate + UDP-glucose
UTPbeta,gammaS + alpha-D-glucose 1-phosphate
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poor substrate, 4.8% of Vmax with diphosphate
UTPbeta,gammaS is chemically unstable and undergoes hydrolysis to UDPbetaS and phosphate, which renders the otherwise reversible reaction irreversible, t1/2 at 25°C: 0.5 min
ir
TTP + alpha-D-glucose 1-phosphate
diphosphate + alpha-TDP-glucose
TTP + alpha-D-glucose 1-phosphate
diphosphate + TDP-glucose
-
-
-
-
r
TTP + alpha-D-glucose 1-phosphate
TDP-glucose + diphosphate
UDP + alpha-D-glucose 1-phosphate
phosphate + UDP-glucose
UDP-D-glucose + diphosphate
UTP + alpha-D-glucose 1-phosphate
-
-
-
r
UDP-glucose + adenosine 5'-tetraphosphate
D-glucose-1-phosphate + adenosyl-5'-pentaphospho-5'-uridine
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-
-
-
?
UDP-glucose + ATP
D-glucose-1-phosphate + adenosyl-5'-tetraphospho-5'-uridine
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-
-
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?
UDP-glucose + CTP
D-glucose-1-phosphate + cytidinyl-5'-tetraphospho-5'-uridine
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-
-
-
?
UDP-glucose + GTP
D-glucose-1-phosphate + guanosyl-5'-tetraphospho-5'-uridine
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-
-
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?
UDP-glucose + guanosine 5'-tetraphosphate
D-glucose-1-phosphate + guanosyl-5'-pentaphospho-5'-uridine
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-
-
-
?
UDP-glucose + tetrapolyphosphate
uridine-5'-pentaphosphate + D-glucose-1-phosphate
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-
-
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?
UDP-glucose + tripolyphosphate
uridine-5'-tetraphosphate + D-glucose-1-phosphate
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-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + alpha-UDP-galactose
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-alpha-D-galactose
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-galactose
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
UDP-D-glucose + diphosphate
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-
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r
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
UTP + D-glucose-1-phosphate
diphosphate + UDP-glucose
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-
-
?
UTP + D-glucose-1-phosphate
UDP-glucose + diphosphate
UTP + glucose-1-phosphate
UDP-glucose + diphosphate
-
-
-
-
?
additional information
?
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ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
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-
-
-
?
CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
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-
?
CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-alpha-D-glucose
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-
-
-
?
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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no activity
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-
?
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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calf and human liver, poor substrate
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r
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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calf and human liver, poor substrate
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r
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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very low activity, wild-type and mutant W218
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r
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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18.5% of the activity with UTP
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r
diphosphate + CDP-glucose
CTP + alpha-D-glucose 1-phosphate
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no activity
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-
?
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
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no activity
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-
?
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
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calf and human liver, poor substrate
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-
r
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
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calf and human liver, poor substrate
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-
r
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
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14.3% of the activity with UTP
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r
diphosphate + GDP-glucose
GTP + alpha-D-glucose 1-phosphate
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no activity
-
-
?
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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no activity
-
-
?
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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calf and human liver
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r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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calf and human liver
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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very low activity, wild-type and mutant W218
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r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
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poor substrate
-
r
diphosphate + TDP-glucose
TTP + alpha-D-glucose 1-phosphate
-
-
-
-
?
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
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-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
?
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
?
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
-
r
diphosphate + UDP-glucose
UTP + alpha-D-glucose 1-phosphate
-
-
-
-
?
diphosphate + UDP-mannose
UTP + D-mannose 1-phosphate
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calf and human liver, poor substrate
-
-
r
diphosphate + UDP-mannose
UTP + D-mannose 1-phosphate
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calf and human liver, poor substrate
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-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
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reaction at 10% the rate of UDP-glucose or UDP-galactose pyrophosphorolysis
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-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
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poor substrate
-
-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
-
calf and human liver
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-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
-
-
-
-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
-
poor substrate
-
-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
-
calf and human liver
-
-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
-
poor substrate
-
-
r
diphosphate + UDP-xylose
UTP + D-xylose 1-phosphate
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calf and human liver
-
-
r
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
-
-
-
-
?
TTP + alpha-D-glucose 1-phosphate
diphosphate + alpha-TDP-glucose
-
-
-
?
TTP + alpha-D-glucose 1-phosphate
diphosphate + alpha-TDP-glucose
-
-
-
?
TTP + alpha-D-glucose 1-phosphate
TDP-glucose + diphosphate
-
-
-
r
TTP + alpha-D-glucose 1-phosphate
TDP-glucose + diphosphate
-
-
-
r
UDP + alpha-D-glucose 1-phosphate
phosphate + UDP-glucose
-
-
-
?
UDP + alpha-D-glucose 1-phosphate
phosphate + UDP-glucose
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + alpha-UDP-galactose
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + alpha-UDP-galactose
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-alpha-D-galactose
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-alpha-D-galactose
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-galactose
-
-
-
r
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-galactose
-
at the same rate as UDP-glucose
-
r
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-galactose
-
about 15% of the activity with UDP-glucose
-
-
r
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-galactose
2.7.7.9 UTP-glucose-1-phosphate uridylyltransferase
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