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Literature summary for 2.7.7.9 extracted from

  • Magee, C.; Nurminskaya, M.; Linsenmayer, T.F.
    UDP-glucose pyrophosphorylase: up-regulation in hypertrophic cartilage and role in hyaluronan synthesis (2001), Biochem. J., 360, 667-674.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in chondrocytes with or without co-transfection of HA synthase gene Gallus gallus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
57000
-
x * 57000, about DNA sequence determination Gallus gallus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Gallus gallus involved in synthesis of hemagglutinin, sulfated proteoglycans, and glycogen in cartilage ?
-
?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cartilage hypertrophic and nonhypertrophic Gallus gallus
-
cell culture of hypertrophic and nonhypertrophic cells and chondrocytes Gallus gallus
-
chondrocyte hypertrophic and nonhypertrophic Gallus gallus
-
embryo
-
Gallus gallus
-
additional information enzyme expression is upregulated in hypertrophic chondrocytes compared to nonhypertrophic chondrocytes, 6fold higher mRNA level Gallus gallus
-
sternum
-
Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in synthesis of hemagglutinin, sulfated proteoglycans, and glycogen in cartilage Gallus gallus ?
-
?
UTP + alpha-D-glucose 1-phosphate
-
Gallus gallus diphosphate + UDP-glucose
-
r

Subunits

Subunits Comment Organism
? x * 57000, about DNA sequence determination Gallus gallus

Synonyms

Synonyms Comment Organism
UGPG-PPase
-
Gallus gallus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
assay at Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
assay at Gallus gallus