Ligand alpha-D-glucose 1-phosphate

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Basic Ligand Information

Molecular Structure
Picture of alpha-D-glucose 1-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H13O9P
alpha-D-glucose 1-phosphate
HXXFSFRBOHSIMQ-VFUOTHLCSA-N
Synonyms:
1-O-phosphono-alpha-D-glucopyranose, alpha-D-glucopyranose 1-phosphate, alpha-D-glucose-1-phosphate, alpha-D-glucose 1 phosphate, alpha-glucose 1-phosphate, D-alpha-glucose 1-phosphate, D-glucose alpha-1-phosphate
Pathway Source
Pathways
MetaCyc
CDP-4-dehydro-3,6-dideoxy-D-glucose biosynthesis, chitin biosynthesis, D-galactose degradation I (Leloir pathway), dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose biosynthesis, dTDP-3-acetamido-alpha-D-fucose biosynthesis more


Show all pahtways known for Show all BRENDA pathways known for alpha-D-glucose 1-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (51 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-D-glucose 1-phosphate + alpha-D-glucose 1-phosphate = maltose + phosphate + phosphate
show the reaction diagram
-
alpha-D-glucose 1-phosphate + D-glucose = cellobiose + phosphate
show the reaction diagram
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(1,3-beta-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate = (1,3-beta-D-glucosyl)n + phosphate
show the reaction diagram
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[(1->2)-beta-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate = [(1->2)-beta-D-glucosyl]n + phosphate
show the reaction diagram
ADP-alpha-D-glucose + alpha-D-glucose-1-phosphate = ADP + alpha-maltose-1-phosphate
show the reaction diagram
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alpha-D-glucopyranose 1-phosphate + D-glycerate = 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
show the reaction diagram
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alpha-D-glucose 1-phosphate + riboflavin = alpha-D-glucose + FMN
show the reaction diagram
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
show the reaction diagram
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CTP + alpha-D-glucose 1-phosphate = diphosphate + CDP-glucose
show the reaction diagram
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alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
show the reaction diagram
alpha-D-Glucose 1-phosphate + D-glucose = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (31 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose
show the reaction diagram
-
-
alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate
show the reaction diagram
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sucrose 6F-phosphate + phosphate = alpha-D-glucopyranose 1-phosphate + beta-D-fructofuranose 6-phosphate
show the reaction diagram
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-
[(1->2)-beta-D-glucosyl]n + phosphate = [(1->2)-beta-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate
show the reaction diagram
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2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate = alpha-D-glucopyranose 1-phosphate + D-glycerate
show the reaction diagram
-
-
(1,4-beta-D-glucosyl)n + phosphate = (1,4-beta-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
show the reaction diagram
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(1,3-beta-D-glucosyl)n + phosphate = (1,3-beta-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate
show the reaction diagram
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-
GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP
show the reaction diagram
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-
6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O = D-glucose alpha-1-phosphate + D-mannosylglycoprotein
show the reaction diagram
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UDP-glucose + H2O = UMP + alpha-D-glucose 1-phosphate
show the reaction diagram
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ADP-glucose + H2O = AMP + alpha-D-glucose 1-phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (374 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-D-glucose 1-phosphate + alpha-D-glucose 1-phosphate = maltose + phosphate + phosphate
show the reaction diagram
-
ADP-alpha-D-glucose + alpha-D-glucose-1-phosphate = ADP + alpha-maltose-1-phosphate
show the reaction diagram
-
alpha-D-glucopyranose 1-phosphate + D-glycerate = 2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate
show the reaction diagram
-
6-deoxy-D-glucose + alpha-D-glucose 1-phosphate = alpha-D-glucopyranosyl 6-deoxy-alpha-D-glucopyranoside + phosphate
show the reaction diagram
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alpha-D-glucose 1-phosphate + riboflavin = alpha-D-glucose + FMN
show the reaction diagram
-
UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose
show the reaction diagram
-
GTP + alpha-D-glucose 1-phosphate = alpha-GDP-glucose + diphosphate
show the reaction diagram
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UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-alpha-D-glucose
show the reaction diagram
alpha-D-glucose 1-phosphate + GDP = GDP-alpha-D-glucose + phosphate
show the reaction diagram
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dGTP + alpha-D-glucose 1-phosphate = diphosphate + dGDP-alpha-D-glucose
show the reaction diagram
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dATP + alpha-D-glucose 1-phosphate = diphosphate + dADP-alpha-D-glucose
show the reaction diagram
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alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate
show the reaction diagram
alpha-D-glucose 1-phosphate + H2O = alpha-D-glucose + phosphate
show the reaction diagram
-
alpha-D-glucose 1-phosphate + H2O = alpha-D-glucose + phosphate
show the reaction diagram
-
alpha-D-glucose 1-phosphate + H2O = alpha-D-glucose + phosphate
show the reaction diagram
-
alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
show the reaction diagram
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alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
show the reaction diagram
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alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
show the reaction diagram

Product in Enzyme-catalyzed Reactions (128 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-O-(alpha-D-glucopyranosyl)-D-glycerate + phosphate = alpha-D-glucopyranose 1-phosphate + D-glycerate
show the reaction diagram
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2-O-(alpha-D-glucopyranosyl)glycerol + phosphate = alpha-D-glucose 1-phosphate + glycerol
show the reaction diagram
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ATP + D-glucose = ADP + alpha-D-glucose 1-phosphate
show the reaction diagram
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diphosphate + ADP-glucose = ATP + alpha-D-glucose 1-phosphate
show the reaction diagram
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diphosphate + UDP-D-glucose = UTP + alpha-D-glucose 1-phosphate
show the reaction diagram
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-
GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP
show the reaction diagram
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-
6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O = D-glucose alpha-1-phosphate + D-mannosylglycoprotein
show the reaction diagram
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ADP-glucose + H2O = AMP + alpha-D-glucose 1-phosphate
show the reaction diagram
-
-
alpha-D-glucose 6-phosphate = alpha-D-glucose 1-phosphate
show the reaction diagram
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-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation
-

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
-
10 mM, 12% inhibition

3D Structure of Enzyme-Ligand-Complex (PDB) (22 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (133 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
14.4
-
pH 6.0, 55C; pH 6.0, 55C
43
-
pH 7.5, 30C, cosubstrate sophorose
96
-
at pH 6.5 and 42C
3
6
pH 6.5, 37C
0.1
-
-
40.43
-
at pH 7.0 and 30C

KM Value (370 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.5
-
-
15.6
-
pH 6.0, 55C; pH 6.0, 55C
1.2
-
pH 7.5, 30C, cosubstrate sophorose
8.1
-
at pH 6.5 and 42C
2.5
-
pH 6.5, 37C
0.021
-
-
0.23
-
-
0.24
-
recombinant His-tagged enzyme, pH and temperature not specified in the publication
2.5
-
-
0.67918
-
at pH 7.0 and 30C

Ki Value (11 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID
0.135
-
pH 8.0, 30C
15929

References & Links