EC Number | Cloned (Comment) | Organism |
---|---|---|
1.5.1.33 | expression in Escherichia coli | Leishmania major |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.5.1.33 | additional information | - |
Leishmania major |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.5.1.33 | additional information | Leishmania major | primary enzyme mediating pteridine salvage | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.5.1.33 | Leishmania major | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.5.1.33 | Biopterin + NADPH | activity with NADH is less than 5% of the activity with NADPH | Leishmania major | 5,6,7,8-Tetrahydrobiopterin + NADP+ | - |
? | |
1.5.1.33 | Dihydrobiopterin + NADPH | - |
Leishmania major | ? | - |
? | |
1.5.1.33 | Dihydrofolate + NADPH | - |
Leishmania major | 5,6,7,8-Tetrahydrofolate + NADP+ | - |
? | |
1.5.1.33 | folate + NADPH | - |
Leishmania major | 5,6,7,8-tetrahydrofolate + NADP+ | - |
? | |
1.5.1.33 | additional information | no activity with quinoid dihydrobiopterin | Leishmania major | ? | - |
? | |
1.5.1.33 | additional information | primary enzyme mediating pteridine salvage | Leishmania major | ? | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.5.1.33 | 4.7 | - |
biopterin as substrate | Leishmania major |
1.5.1.33 | 4.7 | - |
dihydrobiopterin as substrate | Leishmania major |
1.5.1.33 | 6 | - |
dihydrofolate as substrate | Leishmania major |
1.5.1.33 | 6 | - |
folate as substrate | Leishmania major |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.5.1.33 | NADPH | dependent on | Leishmania major |