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Information on EC - protein disulfide-isomerase

for references in articles please use BRENDA:EC5.3.4.1
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EC Tree
     5 Isomerases
         5.3 Intramolecular oxidoreductases
             5.3.4 Transposing S-S bonds
       protein disulfide-isomerase
IUBMB Comments
Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Reaction Schemes
catalyses the rearrangement of -S-S- bonds in proteins
5'-MD, 58 kDa glucose regulated protein, 58 kDa microsomal protein, AGR2, anterior gradient homolog 2, BPA-binding protein, CaBP1, CaBP2, Cellular thyroid hormone binding protein, cotyledon-specific chloroplast biogenesis factor CYO1, more