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Literature summary extracted from

  • Galperin, M.Y.; Moroz, O.V.; Wilson, K.S.; Murzin, A.G.
    House cleaning, a part of good housekeeping (2006), Mol. Microbiol., 59, 5-19.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.1.23 dUTP + H2O Escherichia coli
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Saccharomyces cerevisiae
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Mycobacterium tuberculosis
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Campylobacter jejuni
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Staphylococcus aureus
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Leishmania major
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Trypanosoma cruzi
-
 dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O Mycobacterium tuberculosis H37Rv
-
 dUMP + diphosphate
-
 ?
3.6.1.23 additional information Escherichia coli biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Saccharomyces cerevisiae biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Mycobacterium tuberculosis biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Campylobacter jejuni biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Staphylococcus aureus biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Leishmania major biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Trypanosoma cruzi biological functions in housekeeping, overview ?
-
 ?
3.6.1.23 additional information Mycobacterium tuberculosis H37Rv biological functions in housekeeping, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.6.1.23 Campylobacter jejuni
-
-
-
3.6.1.23 Escherichia coli
-
-
-
3.6.1.23 Leishmania major
-
-
-
3.6.1.23 Mycobacterium tuberculosis P9WNS5
-
-
3.6.1.23 Mycobacterium tuberculosis H37Rv P9WNS5
-
-
3.6.1.23 Saccharomyces cerevisiae
-
-
-
3.6.1.23 Staphylococcus aureus
-
-
-
3.6.1.23 Trypanosoma cruzi
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Escherichia coli
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Saccharomyces cerevisiae
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Mycobacterium tuberculosis
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Campylobacter jejuni
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Staphylococcus aureus
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Leishmania major
a
3.6.1.23 dUTP + H2O = dUMP + diphosphate structural organization and substrate binding modes Trypanosoma cruzi
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.1.23 dUTP + H2O
-
 Escherichia coli dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Saccharomyces cerevisiae dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Mycobacterium tuberculosis dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Campylobacter jejuni dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Staphylococcus aureus dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Leishmania major dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Trypanosoma cruzi dUMP + diphosphate
-
 ?
3.6.1.23 dUTP + H2O
-
 Mycobacterium tuberculosis H37Rv dUMP + diphosphate
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Escherichia coli ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Saccharomyces cerevisiae ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Mycobacterium tuberculosis ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Campylobacter jejuni ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Staphylococcus aureus ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Leishmania major ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Trypanosoma cruzi ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Escherichia coli ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Saccharomyces cerevisiae ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Campylobacter jejuni ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Staphylococcus aureus ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Leishmania major ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Trypanosoma cruzi ?
-
 ?
3.6.1.23 additional information biological functions in housekeeping, overview Mycobacterium tuberculosis H37Rv ?
-
 ?
3.6.1.23 additional information substrate specificity, no hydrolysis of canonical NTPs, overview Mycobacterium tuberculosis H37Rv ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.6.1.23 dimer homodimer Campylobacter jejuni
3.6.1.23 dimer homodimer Staphylococcus aureus
3.6.1.23 dimer homodimer Leishmania major
3.6.1.23 dimer homodimer Trypanosoma cruzi
3.6.1.23 trimer homotrimer Escherichia coli
3.6.1.23 trimer homotrimer Saccharomyces cerevisiae
3.6.1.23 trimer homotrimer Mycobacterium tuberculosis

Synonyms

EC Number Synonyms Comment Organism
3.6.1.23 dUTPase
-
 Escherichia coli
3.6.1.23 dUTPase
-
 Saccharomyces cerevisiae
3.6.1.23 dUTPase
-
 Mycobacterium tuberculosis
3.6.1.23 dUTPase
-
 Campylobacter jejuni
3.6.1.23 dUTPase
-
 Staphylococcus aureus
3.6.1.23 dUTPase
-
 Leishmania major
3.6.1.23 dUTPase
-
 Trypanosoma cruzi
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Escherichia coli
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Saccharomyces cerevisiae
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Mycobacterium tuberculosis
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Campylobacter jejuni
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Staphylococcus aureus
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Leishmania major
3.6.1.23 additional information the enzyme belongs to the Nudix superfamily of enzymes Trypanosoma cruzi