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Information on EC 1.14.11.6 - thymine dioxygenase

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IUBMB Comments
Requires Fe2+ and ascorbate. Also acts on 5-hydroxymethyluracil to oxidize its -CH2OH group first to -CHO and then to -COOH.
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The enzyme appears in viruses and cellular organisms
Synonyms
5-hydroxy-methyluracil dioxygenase, 5-hydroxy-methyluracil oxygenase, Fe2+/2-oxoglutarate dependent hydroxylase, J binding protein 1, J binding protein 2, J-binding protein 1, J-binding protein 2, JBP1, JBP2, More, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2
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