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Literature summary extracted from

  • Mueller, K.E.; Zampieri, R.A.; Aoki, J.I.; Muxel, S.M.; Nerland, A.H.; Floeter-Winter, L.M.
    Amino acid permease 3 (aap3) coding sequence as a target for Leishmania identification and diagnosis of leishmaniases using high resolution melting analysis (2018), Parasit. Vectors, 11, 421 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania mexicana
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania amazonensis
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania major
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania braziliensis
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania tropica
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania donovani
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania infantum
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania guyanensis
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania lainsoni
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania naiffi
7.4.2.1 medicine the enzyme is used as a target for Leishmania identification and diagnosis of leishmaniases Leishmania shawi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania mexicana
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania amazonensis
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania major
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania braziliensis
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania tropica
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania donovani
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania infantum
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania guyanensis
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania lainsoni
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania naiffi
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1] Leishmania shawi
-
 ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.4.2.1 Leishmania amazonensis
-
-
-
7.4.2.1 Leishmania braziliensis
-
-
-
7.4.2.1 Leishmania donovani Q86G79
-
-
7.4.2.1 Leishmania guyanensis
-
-
-
7.4.2.1 Leishmania infantum A4I6I1
-
-
7.4.2.1 Leishmania lainsoni
-
-
-
7.4.2.1 Leishmania major
-
-
-
7.4.2.1 Leishmania mexicana
-
-
-
7.4.2.1 Leishmania naiffi
-
-
-
7.4.2.1 Leishmania shawi
-
-
-
7.4.2.1 Leishmania tropica
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.4.2.1 promastigote
-
 Leishmania mexicana
-
7.4.2.1 promastigote
-
 Leishmania amazonensis
-
7.4.2.1 promastigote
-
 Leishmania major
-
7.4.2.1 promastigote
-
 Leishmania braziliensis
-
7.4.2.1 promastigote
-
 Leishmania tropica
-
7.4.2.1 promastigote
-
 Leishmania donovani
-
7.4.2.1 promastigote
-
 Leishmania infantum
-
7.4.2.1 promastigote
-
 Leishmania guyanensis
-
7.4.2.1 promastigote
-
 Leishmania lainsoni
-
7.4.2.1 promastigote
-
 Leishmania naiffi
-
7.4.2.1 promastigote
-
 Leishmania shawi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania mexicana ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania amazonensis ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania major ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania braziliensis ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania tropica ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania donovani ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania infantum ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania guyanensis ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania lainsoni ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania naiffi ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?
7.4.2.1 ATP + H2O + L-arginine-[L-arginine-binding protein][side 1]
-
 Leishmania shawi ADP + phosphate + L-arginine[side 2] + [L-arginine-binding protein][side 1]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
7.4.2.1 aap3
-
 Leishmania mexicana
7.4.2.1 aap3
-
 Leishmania amazonensis
7.4.2.1 aap3
-
 Leishmania major
7.4.2.1 aap3
-
 Leishmania braziliensis
7.4.2.1 aap3
-
 Leishmania tropica
7.4.2.1 aap3
-
 Leishmania donovani
7.4.2.1 aap3
-
 Leishmania infantum
7.4.2.1 aap3
-
 Leishmania guyanensis
7.4.2.1 aap3
-
 Leishmania lainsoni
7.4.2.1 aap3
-
 Leishmania naiffi
7.4.2.1 aap3
-
 Leishmania shawi
7.4.2.1 amino acid permease 3
-
 Leishmania mexicana
7.4.2.1 amino acid permease 3
-
 Leishmania amazonensis
7.4.2.1 amino acid permease 3
-
 Leishmania major
7.4.2.1 amino acid permease 3
-
 Leishmania braziliensis
7.4.2.1 amino acid permease 3
-
 Leishmania tropica
7.4.2.1 amino acid permease 3
-
 Leishmania donovani
7.4.2.1 amino acid permease 3
-
 Leishmania infantum
7.4.2.1 amino acid permease 3
-
 Leishmania guyanensis
7.4.2.1 amino acid permease 3
-
 Leishmania lainsoni
7.4.2.1 amino acid permease 3
-
 Leishmania naiffi
7.4.2.1 amino acid permease 3
-
 Leishmania shawi