Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Filter enzyme data
show all tables | show all data
hide all tables
No. of entries

Information on EC 3.13.2.1 - adenosylhomocysteinase

for references in articles please use BRENDA:EC3.13.2.1

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

The enzyme contains one tightly bound NAD+ per subunit. This appears to bring about a transient oxidation at C-3′ of the 5′-deoxyadenosine residue, thus labilizing the thioether bond (for mechanism, click here), cf. EC 5.5.1.4, inositol-3-phosphate synthase.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
s-adenosylhomocysteine hydrolase, adohcy hydrolase, s-adenosyl-l-homocysteine hydrolase, sah hydrolase, adohcyase, sahase, adenosylhomocysteinase, s-adenosylhomocysteinase, pfsahh, s-adenosyl homocysteine hydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
L-methionine degradation I (to L-homocysteine), S-adenosyl-L-methionine salvage II