EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
glioma cell |
- |
761332 |
1.1.1.41 | isocitrate dehydrogenase (NAD+) |
glioma cell |
- |
712180 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
glioma cell |
- |
712180, 712574, 712614, 713113, 739984 |
1.13.11.31 | arachidonate 12-lipoxygenase |
glioma cell |
- |
688759 |
1.13.11.34 | arachidonate 5-lipoxygenase |
glioma cell |
- |
688512 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
glioma cell |
- |
756531 |
1.14.14.14 | aromatase |
glioma cell |
- |
726047 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
glioma cell |
- |
690140 |
1.14.15.18 | calcidiol 1-monooxygenase |
glioma cell |
- |
659811 |
1.14.16.4 | tryptophan 5-monooxygenase |
glioma cell |
- |
687604 |
1.14.19.17 | sphingolipid 4-desaturase |
glioma cell |
- |
744686 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
glioma cell |
- |
741427 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
glioma cell |
- |
673219, 701644, 705897 |
2.3.1.299 | sphingoid base N-stearoyltransferase |
glioma cell |
- |
757888 |
2.3.1.48 | histone acetyltransferase |
glioma cell |
- |
756850 |
2.3.1.57 | diamine N-acetyltransferase |
glioma cell |
- |
757876 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
glioma cell |
- |
736507 |
2.4.1.224 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase |
glioma cell |
- |
759360 |
2.4.1.225 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase |
glioma cell |
- |
759360 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
glioma cell |
- |
685932, 718736 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
glioma cell |
- |
735872 |
2.5.1.26 | alkylglycerone-phosphate synthase |
glioma cell |
- |
737578, 739210 |
2.6.1.42 | branched-chain-amino-acid transaminase |
glioma cell |
- |
758657 |
2.7.1.105 | 6-phosphofructo-2-kinase |
glioma cell |
- |
739621, 761915 |
2.7.1.137 | phosphatidylinositol 3-kinase |
glioma cell |
- |
709276 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
glioma cell |
- |
709907 |
2.7.1.94 | acylglycerol kinase |
glioma cell |
- |
761230 |
2.7.10.2 | non-specific protein-tyrosine kinase |
glioma cell |
- |
721489 |
2.7.11.11 | cAMP-dependent protein kinase |
glioma cell |
- |
662380 |
2.7.11.13 | protein kinase C |
glioma cell |
- |
676323 |
2.7.11.20 | elongation factor 2 kinase |
glioma cell |
- |
760810 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
glioma cell |
- |
760351 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
glioma cell |
- |
645316 |
2.7.8.27 | sphingomyelin synthase |
glioma cell |
- |
737747 |
2.8.2.17 | chondroitin 6-sulfotransferase |
glioma cell |
- |
761061 |
2.8.2.23 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 |
glioma cell |
- |
759360 |
2.8.2.29 | [heparan sulfate]-glucosamine 3-sulfotransferase 2 |
glioma cell |
- |
759360 |
2.8.2.8 | [heparan sulfate]-glucosamine N-sulfotransferase |
glioma cell |
- |
759360 |
3.1.3.16 | protein-serine/threonine phosphatase |
glioma cell |
- |
692085, 750280 |
3.1.3.5 | 5'-nucleotidase |
glioma cell |
- |
694138 |
3.1.3.77 | acireductone synthase |
glioma cell |
- |
751767 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
glioma cell |
- |
135401 |
3.1.4.4 | phospholipase D |
glioma cell |
- |
708012 |
3.1.6.13 | iduronate-2-sulfatase |
glioma cell |
- |
650371 |
3.2.1.166 | heparanase |
glioma cell |
- |
693320, 759360 |
3.2.1.45 | glucosylceramidase |
glioma cell |
- |
751699 |
3.3.2.6 | leukotriene-A4 hydrolase |
glioma cell |
- |
752495 |
3.4.14.5 | dipeptidyl-peptidase IV |
glioma cell |
- |
703784 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
glioma cell |
- |
710451 |
3.4.21.109 | matriptase |
glioma cell |
- |
717799 |
3.4.21.26 | prolyl oligopeptidase |
glioma cell |
- |
669933, 683344 |
3.4.21.73 | u-Plasminogen activator |
glioma cell |
- |
710121 |
3.4.21.75 | Furin |
glioma cell |
- |
708753 |
3.4.21.B28 | fibroblast activation protein alpha subunit |
glioma cell |
- |
707629 |
3.4.22.15 | cathepsin L |
glioma cell |
- |
712921 |
3.4.22.60 | caspase-7 |
glioma cell |
- |
700938 |
3.4.22.61 | caspase-8 |
glioma cell |
- |
664508 |
3.4.22.62 | caspase-9 |
glioma cell |
- |
665736 |
3.4.22.B70 | SENP1 peptidase |
glioma cell |
- |
753729 |
3.4.24.17 | stromelysin 1 |
glioma cell |
- |
708089 |
3.4.24.82 | ADAMTS-4 endopeptidase |
glioma cell |
- |
638956 |
3.4.24.B4 | matrix metalloproteinase-13 |
glioma cell |
- |
711163 |
3.4.24.B7 | matrix metalloproteinase-26 |
glioma cell |
- |
713160, 754946 |
3.6.1.9 | nucleotide diphosphatase |
glioma cell |
- |
246803 |
4.1.1.17 | ornithine decarboxylase |
glioma cell |
- |
680217, 682982, 697101, 697861 |
4.3.2.9 | gamma-glutamylcyclotransferase |
glioma cell |
- |
735619 |
4.4.1.5 | lactoylglutathione lyase |
glioma cell |
- |
709654 |
4.6.1.1 | adenylate cyclase |
glioma cell |
- |
694258 |
5.1.1.18 | serine racemase |
glioma cell |
- |
705283 |
5.1.3.17 | heparosan-N-sulfate-glucuronate 5-epimerase |
glioma cell |
- |
759360 |
5.3.99.3 | prostaglandin-E synthase |
glioma cell |
- |
681868 |
5.3.99.5 | thromboxane-A synthase |
glioma cell |
- |
705275 |
5.4.2.11 | phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) |
glioma cell |
- |
748795 |
6.3.1.2 | glutamine synthetase |
glioma cell |
- |
671608, 745832 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
glioma cell |
- |
745756 |
1.4.3.4 | monoamine oxidase |
glioma cell |
activity selectively increases in MAO-B activity in human gliomas when compared with meningiomas or non-tumoural tissue |
689175 |
3.4.22.1 | cathepsin B |
glioma cell |
astrocytic |
707558 |
1.2.1.24 | succinate-semialdehyde dehydrogenase (NAD+) |
glioma cell |
astrocytomas and oligodendrogliomas |
763330 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
glioma cell |
biopsies |
688740 |
3.1.4.12 | sphingomyelin phosphodiesterase |
glioma cell |
C6-glioma cells |
652974 |
3.1.4.11 | phosphoinositide phospholipase C |
glioma cell |
C6Bu-1 rat glioma cell, isoenzyme PI-PLC-beta1 |
668867 |
2.4.1.212 | hyaluronan synthase |
glioma cell |
cell line |
395258 |
2.4.1.101 | alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
glioma cell |
cell proliferation and migration analysis, overview |
759196 |
2.4.1.175 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase |
glioma cell |
CHSY1 is frequently upregulated in glioblastoma and correlates with high tumor grade and poor survival |
759875 |
2.4.1.226 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase |
glioma cell |
CHSY1 is frequently upregulated in glioblastoma and correlates with high tumor grade and poor survival |
759875 |
2.7.1.3 | ketohexokinase |
glioma cell |
expressed at significantly higher level in glioma tissues than in non-tumor brain |
758732 |
2.1.2.1 | glycine hydroxymethyltransferase |
glioma cell |
expression of SHMT2 in ischemic tumor zones |
736882 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
glioma cell |
gene expression profiling reveals that GLUD2 is selectively and consistently upregulated in glioma cells harboring IDH mutations |
762783 |
2.7.1.1 | hexokinase |
glioma cell |
hexokinase I, predominant in normal brain |
640259 |
2.7.1.1 | hexokinase |
glioma cell |
hexokinase II, increased in brain tumors, ethylnitrosourea-induced 36B-10 astrocytic F-344 rat brain tumor cell line |
640259 |
1.13.11.34 | arachidonate 5-lipoxygenase |
glioma cell |
high enzyme expression level |
686278 |
3.4.24.24 | gelatinase A |
glioma cell |
high expression level of MMP-2 increasing during growth |
683427 |
3.4.24.35 | gelatinase B |
glioma cell |
high expression level of MMP-9 increasing during growth |
683427 |
1.1.1.300 | NADP-retinol dehydrogenase |
glioma cell |
high RDH10 expression level, 13.89%, 43.59%, 70.59%, and 90.24% expression of RDH10 in glioma of grade I, II, III, and IV (WHO grading), respectively |
762073 |
3.4.24.23 | matrilysin |
glioma cell |
highly variable MMP-7 expression in the glioma population |
683864 |
3.6.1.9 | nucleotide diphosphatase |
glioma cell |
homologue to plasma cell membrane glycoprotein PC-1 |
246804 |
2.4.1.47 | N-acylsphingosine galactosyltransferase |
glioma cell |
human fetal glioma cell line |
489221 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
glioma cell |
human glioma cell line HTB-138, InsP3 3-kinase B mRNA |
640751 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
glioma cell |
IDH1, diffuse gliomas graded II-IV |
713508 |
3.1.3.7 | 3'(2'),5'-bisphosphate nucleotidase |
glioma cell |
in glioma tissues, phosphocholine(36:1) is not detected and 3'-phosphoadenylate (pAp) content is significantly increased. The gene expression of the 3'-nucleotidase 3'(2'),5'-bisphosphate nucleotidase 1 (BPNT-1) is dramatically downregulated, quantitative real-time polymerase chain reaction (qRT-PCR) expression analysis. Gene expression of enzymes associated with pAp metabolism |
752237 |