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Information on EC 1.13.11.31 - arachidonate 12-lipoxygenase

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IUBMB Comments
The product is rapidly reduced to the corresponding 12S-hydroxy compound.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
12-lipoxygenase, 15-lipoxygenase, 12-lox, 12-lo, 15-lo, alox5, alox15, 12/15-lipoxygenase, 12/15-lo, 12/15-lox, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
arachidonate + O2 = (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
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PATHWAY SOURCE
PATHWAYS