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Information on EC 2.7.1.153 - phosphatidylinositol-4,5-bisphosphate 3-kinase

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IUBMB Comments
This enzyme also catalyses the phosphorylation of PtdIns4P to PtdIns(3,4)P2, and of PtdIns to PtdIns3P. Four mammalian isoforms are known to exist.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
pik3ca, pi 3-kinase, phosphoinositide 3-kinase, pi3-kinase, pi3-k, pi-3k, phosphatidylinositol 3'-kinase, p110alpha, pi 3-k, pi3kgamma, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate
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PATHWAY SOURCE
PATHWAYS