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Information on EC 3.4.21.73 - u-Plasminogen activator

for references in articles please use BRENDA:EC3.4.21.73

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IUBMB Comments

Formed from the inactive precursor by action of plasmin or plasma kallikrein. Differs in structure from t-plasminogen activator (EC 3.4.21.68), and does not bind to fibrin. In peptidase family S1 (trypsin family). Formerly included in EC 3.4.21.31 and EC 3.4.99.26

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
Specific cleavage of Arg-/-Val bond in plasminogen to form plasmin

Synonyms
urokinase, urokinase-type plasminogen activator, urokinase plasminogen activator, urokinase type plasminogen activator, urokinase-type pa, urokinase-type plasminogen, urokinase-plasminogen activator, urinary plasminogen activator, cellular plasminogen activator, two-chain urokinase-type plasminogen activator, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Specific cleavage of Arg-/-Val bond in plasminogen to form plasmin
show the reaction diagram
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