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Literature summary for 3.4.21.73 extracted from
- Inhibition of integrin alphavbeta3 prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia (2009), Am. J. Physiol. Heart Circ. Physiol., 296, H862-H867.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in S2 cells | Sus scrofa |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
recombinant uPA, native PAGE | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
piglets | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant uPA from S2 cells by immunoaffinity chromatography | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 50000, recombinant uPA, SDS-PAGE | Sus scrofa |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| uPA | - |
Sus scrofa |
| Urokinase plasminogen activator | - |
Sus scrofa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | urokinase plasminogen activator mediates impairment of hypercapnic and hypotensive cerebrovasodilation and pial artery dilation after cerebral hypoxia/ischemia, which is prevented by inhibition of integrin alphanubeta3, overview. Inhibition of uPA and integrin signaling may preserve cerebrohemodynamic control after hypoxia/ischemia | Sus scrofa |
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Release 2023.1 (January 2023)
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