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EC Number
Source Tissue
Commentary
Reference
3.4.21.73
22Rv1 cell
silencing of transmembrane protein Notch1 by siRNA results in significant reduction in the expression of uPA and matrix metalloproteinase-9 gene transcripts. Knock-down of Notch also reduces the mRNA expression and protein levels of uPA and matrix metalloproteinase-9
697383
3.4.21.73
A-2058 cell
melanoma cell
667189
3.4.21.73
A-431 cell
-
29573
,
29660
,
29661
3.4.21.73
A-431 cell
A431 epidermoid carcinoma cells
29671
3.4.21.73
A-549 cell
-
699131
3.4.21.73
A-549 cell
A-549 alveolar epithelial cell cultured on a fibrin matrix, stimulation by interleukin 1beta results in increased levels of enzyme in culture supernatant
670938
3.4.21.73
alveolar cell
-
29663
3.4.21.73
blood plasma
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-
,
669742
,
696963
,
699162
,
731237
3.4.21.73
blood plasma
patients with common variable immunodeficiency show increased levels of plasma uPA
697422
3.4.21.73
blood platelet
uPA shows extensive colocalization with alpha-granule proteins in both cultured Quebec platelet disease megakaryocytes and platelets, and with plasminogen in Quebec platelet disease platelets
696942
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