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BRENDA support

Literature summary for 3.4.21.73 extracted from

  • Patel, T.H.; Sprague, S.; Lai, Q.; Jimenez, D.F.; Barone, C.M.; Ding, Y.
    Blood brain barrier (BBB) dysfunction associated with increased expression of tissue and urokinase plasminogen activators following peripheral thermal injury (2008), Neurosci. Lett., 444, 222-226.
    View publication on PubMed

Application

Application Comment Organism
medicine brain tissue of thermally injured rats displays an increase in the brain water content and the presence of Evans blue, temporally associated with an increased expression of endogenous tPA and uPA. Peripheral thermal injury does induce an increase in the permeability of the blood brain barrier Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
brain brain tissue of thermally injured rats displays an increase in the brain water content and the presence of Evans blue, temporally associated with an increased expression of endogenous tPA and uPA. Peripheral thermal injury does induce an increase in the permeability of the blood brain barrier Rattus norvegicus
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