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Information on EC 3.6.1.9 - nucleotide diphosphatase

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EC Tree
     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.9 nucleotide diphosphatase
IUBMB Comments
The enzyme preferentially hydrolyses ATP, but can also hydrolyse other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates. In vitro the enzyme also acts as a nucleotidohydrolase on ADP, NAD+, NADP+, FAD, and CoA.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
npp, cd203c, itpase, inosine triphosphate pyrophosphatase, nppase, e-npp, enpp3, nucleoside triphosphate pyrophosphohydrolase, e-npp3, ecto-nucleotide pyrophosphatase/phosphodiesterase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a nucleoside triphosphate + H2O = a nucleotide + diphosphate
show the reaction diagram