Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-phospho-D-glycerate | Homo sapiens | - |
3-phospho-D-glycerate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P18669 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
glioma cell | - |
Homo sapiens | - |
U-87 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-phospho-D-glycerate | - |
Homo sapiens | 3-phospho-D-glycerate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PGAM1 | - |
Homo sapiens |
phosphoglycerate mutase 1 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the mRNA and protein expression of the enzyme is significantly greater in glioma than normal brain tissues | up |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme knockdown significantly inhibits glioma cell proliferation, promotes glioma cell apoptosis, induces S phase cell cycle arrest and inhibits glioma cell migration and invasion in vitro | Homo sapiens |
physiological function | the enzyme is associated with the grade of glioma and is involved in the biological behavior of glioma cells | Homo sapiens |