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Literature summary for 2.7.1.127 extracted from

  • Vanweyenberg, V.; Communi, D.; D'Santos, C.S.; Erneux, C.
    Tissue- and cell-specific expression of Ins(1,4,5)P3 3-kinase isoenzymes (1995), Biochem. J., 306, 429-435.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.127

Cloned(Commentary)

Cloned (Comment) Organism
a cDNA encoding InsP3 3-kinase B is cloned from a thymus cDNA library and expressed in Escherichia coli, sequence of the 673 amino acids protein Rattus norvegicus
cDNA encoding InsP3 3-kinase B is cloned from a hippocampus cDNA library and expressed in Escherichia coli, amino acid sequence Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Homo sapiens
-
-
soluble
-
 Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activation by Ca2+/calmodulin Homo sapiens
Ca2+ activation by Ca2+/calmodulin Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 2 isoenzymes: A and B
-
Rattus norvegicus
-
 2 isoenzymes: A and B
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
brain InsP3 3-kinase A and B mRNA Rattus norvegicus
-
glioma cell human glioma cell line HTB-138, InsP3 3-kinase B mRNA Homo sapiens
-
heart InsP3 3-kinase B mRNA Rattus norvegicus
-
HL-60 cell non-differentiated promyelocytic-leukaemia cell line, InsP3 3-kinase B mRNA Homo sapiens
-
lung predominant expression of InsP3 3-kinase B mRNA in lung Rattus norvegicus
-
additional information isoenzymes A and B are specifically expressed in different tissues and cells, expression pattern Homo sapiens
-
additional information isoenzymes A and B are specifically expressed in different tissues and cells, expression pattern Rattus norvegicus
-
neuroblastoma cell line human cell line SH-SY5Y, InsP3 3-kinase B mRNA Homo sapiens
-
testis InsP3 3-kinase A and B mRNA Rattus norvegicus
-
thymus isolation of a cDNA clone encoding InsP3 3-kinase B from a thymus cDNA library Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1D-myo-inositol 1,4,5-trisphosphate
-
 Homo sapiens ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?
ATP + 1D-myo-inositol 1,4,5-trisphosphate
-
 Rattus norvegicus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Homo sapiens
ATP
-
 Rattus norvegicus
Calmodulin activation by Ca2+/calmodulin Homo sapiens
Calmodulin activation by Ca2+/calmodulin Rattus norvegicus