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Information on EC 3.1.4.12 - sphingomyelin phosphodiesterase

for references in articles please use BRENDA:EC3.1.4.12

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IUBMB Comments

Has very little activity on phosphatidylcholine.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

Synonyms
sphingomyelinase, alpha-toxin, acid sphingomyelinase, smase, neutral sphingomyelinase, asmase, nsmase2, nsmase, n-smase, smpd1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a sphingomyelin + H2O = a ceramide + phosphocholine
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
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