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Literature summary for 3.1.4.12 extracted from
- Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha (2005), J. Orthop. Res., 23, 1258-1265.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | the sphingomyelin cycle is a potential therapeutic target for the prevention of wear debris induced osteolysis | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | spingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ANA-1 cell | murine macrophage cell line | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | spingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis | Mus musculus | ? | - |
? | |
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Release 2023.1 (January 2023)
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