Application | Comment | Organism |
---|---|---|
medicine | systemic administration of recombinant acid sphingomyelinase (rhASM) into ASM deficient mice by intranasal instillation results in hydrolysis of the abnormal storage of sphingomyelin in lysosomes of the liver, spleen and lung, pulmonary administration of rhASM may represent an alternative route of delivery to address the visceral pathology associated with ASM deficiency | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
sphingomyelin + H2O | - |
Homo sapiens | N-acylsphingosine + choline phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid sphingomyelinase | - |
Homo sapiens |
ASM | - |
Homo sapiens |