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Information on EC 2.7.1.1 - hexokinase

for references in articles please use BRENDA:EC2.7.1.1

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IUBMB Comments

D-Glucose, D-mannose, D-fructose, sorbitol and D-glucosamine can act as acceptors; ITP and dATP can act as donors. The liver isoenzyme has sometimes been called glucokinase.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
hexokinase, hexokinase ii, hexokinase 2, hexokinase i, hk ii, hxk, liver glucokinase, hexokinase 1, hexokinase-2, hkdc1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + D-glucose = ADP + D-glucose 6-phosphate
show the reaction diagram
ATP + D-hexose = ADP + D-hexose 6-phosphate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
BRENDA
MetaCyc
1,3-propanediol biosynthesis (engineered), Bifidobacterium shunt, GDP-alpha-D-glucose biosynthesis, glucose and glucose-1-phosphate degradation, glycogen degradation I, glycogen degradation II, glycolysis III (from glucose), heterolactic fermentation, sucrose biosynthesis II, sucrose degradation III (sucrose invertase), trehalose degradation I (low osmolarity), trehalose degradation II (cytosolic), trehalose degradation IV, trehalose degradation V, UDP-N-acetyl-D-galactosamine biosynthesis II, UDP-N-acetyl-D-glucosamine biosynthesis II