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Information on EC - protein kinase C

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IUBMB Comments
A family of serine- and threonine-specific protein kinases that depend on lipids for activity. They can be activated by calcium but have a requirement for the second messenger diacylglycerol. Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell-signalling pathways. Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumour promoters.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
alpha-PKC, aPKCzeta, AS PKCdelta, ATP analog specific protein kinase Cdelta, C1Bbeta, Calcium-dependent protein kinase C, calcium-independent protein kinase C, Capkc1p, epsilonPKC, More, more
ATP + a protein = ADP + a phosphoprotein
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