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2,4-dinitrophenyl-GARFW-OH + H2O
?
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?
2,4-dinitrophenyl-GDRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GERFW-OH + H2O
?
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-
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?
2,4-dinitrophenyl-GFAFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFDFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFEFW-OH + H2O
?
-
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?
2,4-dinitrophenyl-GFFFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFGFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFHFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFIFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFKFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFLFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFPFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFQFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRAW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRDW-OH + H2O
?
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?
2,4-dinitrophenyl-GFREW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRGW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRHW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRIW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRKW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRLW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRPW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRQW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRRW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRSW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRVW-OH + H2O
?
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?
2,4-dinitrophenyl-GFRW R-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWA-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWD-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWE-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWF-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWG-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWI-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWK-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWL-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWP-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWQ-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWS-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWV-OH + H2O
?
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?
2,4-dinitrophenyl-GFRWY-OH + H2O
?
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?
2,4-dinitrophenyl-GFRYW-OH + H2O
?
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?
2,4-dinitrophenyl-GFSFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFVFW-OH + H2O
?
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?
2,4-dinitrophenyl-GFYFW-OH + H2O
?
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?
2,4-dinitrophenyl-GGRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GHRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GIRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GKRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GLRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GPRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GQRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GRRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GSRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GVRFW-OH + H2O
?
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?
2,4-dinitrophenyl-GYRFW-OH + H2O
?
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?
2-aminobenzoyl-Gly-Ile-Val-Arg-Ala-(Nepsilon-2,4-dinitrophenyl)Lys + H2O
2-aminobenzoyl-Gly-Ile-Val-Arg + Ala-(Nepsilon-2,4-dinitrophenyl)Lys
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an exoproteolytic substrate
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?
2-aminobenzoyl-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH + H2O
?
4-(4-dimethylaminophenylazo)benzoyl-IEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-IEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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no hydrolysis at pH 6.0
-
?
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-D-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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?
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Arg-L-Leu-L-Arg-Gly-L-Phe-L-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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?
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-D-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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?
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-L-Leu-L-Arg-Gly-L-Phe-L-Glu + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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?
4-(4-dimethylaminophenylazo)benzoyl-LEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-LEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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no hydrolysis at pH 6.0
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?
4-(4-dimethylaminophenylazo)benzoyl-LRGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-LRGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
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?
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RIEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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?
4-(4-dimethylaminophenylazo)benzoyl-RIIEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RIIEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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no hydrolysis at pH 6.0
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLEGIE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
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?
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVG-beta-(2-naphthyl)alanine-E + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
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?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFD + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
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?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
-
?
4-(4-dimethylaminophenylazo)benzoyl-RLVGFL-alpha-aminoadipic acid-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGFL-alpha-aminoadipic acid + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
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?
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE-5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid + H2O
4-(4-dimethylaminophenylazo)benzoyl-RLVGWE + 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid
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-
-
?
5-amino-1-(phenylsulfonyl)-1H-pyrazol-3-yl thiophene-2-carboxylate + H2O
5-amino-1-(phenylsulfonyl)-1,2-dihydro-3H-pyrazol-3-one + thiophene-2-carbaldehyde
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-
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?
5-amino-1-[(4-methoxyphenyl)sulfonyl]-1H-pyrazol-3-yl pyridine-4-carboxylate + H2O
5-amino-1-[(4-methoxyphenyl)sulfonyl]-1,2-dihydro-3H-pyrazol-3-one + pyridine-4-carbaldehyde
-
-
-
-
?
5-dimethylaminonaphthalene-1-sulfonyl-Phe-Arg-Phe(NO2)-Leu + H2O
?
pH 6.4, 37°C, 2 mM cysteine, 1 mM EDTA
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-
?
6-maleimidocaproic acid-L-Arg-Arg-Ala-Leu-Ala-Leu-Ala-camptothecin + H2O
?
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major cleavage products are L-Leu-Ala-Leu-Ala-camptothecin, L-Ala-Leu-Ala-camptothecin, L-Leu-Ala-camptothecin, and camptothecin
-
?
6-maleimidocaproic acid-L-Arg-Arg-Ala-Leu-Ala-Leu-doxorubicin + H2O
?
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major cleavage products are L-Leu-Ala-Leu-doxorubicin, L-Leu-doxorubicin, and doxorubicin
-
?
Abeta peptide + H2O
?
the enzyme cleaves the Abeta peptide from the carboxylic end of Glu11
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-
?
Abz-Ala-Phe-Arg-Ser-Ala-X-Gln-EDDnp + H2O
Abz-Ala-Phe-Arg + Ser-Ala-X-Gln-EDDnp
kcat/Km for Abz-Ala-Phe-Arg-Ser-Ala-X-Gln-EDDnp, with X is Asn > Tyr, His, Leu, Trp > Ser, Phe, Pro Lys > Asp, Ala
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-
?
Abz-Ala-Phe-Arg-Ser-X-Arg-Ser-Ala-Gln-EDDnp + H2O
Abz-Ala-Phe-Arg + Ser-X-Arg-Ser-Ala-Gln-EDDnp
kcat/Km for Abz-Ala-Phe-Arg-Ser-X-Arg-Ser-Ala-Gln-EDDnp, with X is Asn > Trp, Tyr, Ala > Ser, Phe > His, Lys > Asp, Leu, Pro
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-
?
Abz-Ala-X-Ala-Phe-Arg-Ser-Ala-Gln-EDDnp + H2O
Abz-Ala-X-Ala-Phe-Arg + Ser-Ala-Gln-EDDnp
kcat/Km for Abz-Ala-X-Ala-Phe-Arg-Ser-Ala-Gln-EDDnp, with X is Leu, Tyr > Phe, Ala, Ser, Pro > His, Lys > Asn, Asp
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-
?
Abz-Ala-X-Arg-Ser-Ala-Ala-Gln-EDDnp + H2O
Abz-Ala-X-Arg + Ser-Ala-Ala-Gln-EDDnp
kcat/Km for Abz-Ala-X-Arg-Ser-Ala-Ala-Gln-EDDnp, with X is Phe, Leu > Arg > Ala > Pro
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-
?
Abz-FF-3-dinitrophenyl-2,3-diaminopropionic acid-W-OH + H2O
?
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?
Abz-FR-3-dinitrophenyl-2,3-diaminopropionic acid-W-OH + H2O
?
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?
Abz-FR-epsilon-dinitrophenyl-L-lysyl-2,3-diaminopropionic acid-P-OH + H2O
?
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?
Abz-FR-epsilon-dinitrophenyl-L-lysyl-2,3-diaminopropionic acid-W-OH + H2O
?
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?
Abz-FRA-epsilon-dinitrophenyl-L-lysyl-2,3-diaminopropionic acid-OH + H2O
?
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?
Abz-FRF(NO2)A + H2O
?
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?
Abz-FRF-epsilon-dinitrophenyl-L-lysyl-2,3-diaminopropionic acid-OH + H2O
?
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?
Abz-GIVRAK(Dnp)-OH + H2O
?
200 mM NaCl, 2.5 mM DTT, pH 4.5, 37°C
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-
?
3.4.22.1 cathepsin B
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