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Literature summary for 3.4.22.1 extracted from

  • Gogiel, T.; Galewska, Z.; Romanowicz, L.
    Differential distribution of cathepsin B in human umbilical cord tissues (2012), Acta Biochim. Pol., 59, 679-684.
    View publication on PubMed
Search for more literature for 3.4.22.1

Inhibitors

Inhibitors Comment Organism Structure
L-3-trans-propylcarbamoyloxirane-2-carbonyl-L-isoleucyl-proline
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
 SDS-PAGE, mature cathepsin B Homo sapiens
42000
-
 SDS-PAGE, procathepsin B Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P07858
-
-

Source Tissue

Source Tissue Comment Organism Textmining
umbilical cord highest expression in Wharton's jelly and the lowest in the umbilical cord arteries Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 total cathepsin B activity and content calculated per gram of DNA are higher in Wharton's jelly than in the umbilical cord vessels Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-CBZ-L-Arg-L-Arg-7-amido- 4-methylcoumarin + H2O
-
 Homo sapiens N-CBZ-L-Arg-L-Arg + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
CatB
-
 Homo sapiens
cathepsin B
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Homo sapiens

Expression

Organism Comment Expression
Homo sapiens highest expression in Wharton's jelly and the lowest in the umbilical cord arteries up