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Literature summary for 3.4.22.1 extracted from

  • Gunatilleke, S.S.; de Oliveira, C.A.; McCammon, J.A.; Barrios, A.M.
    Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study (2008), J. Biol. Inorg. Chem., 13, 555-561.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(triethylphosphine)gold(I) chloride
-
Homo sapiens
chloro(diethylphenylphosphine)gold(I)
-
Homo sapiens
chloro(ethyldiphenylphosphine)gold(I)
-
Homo sapiens
chloro(triphenylphosphine)gold(I)
-
Homo sapiens
triethylphosphine(2,3,4,6-tetra-O-acetyl-beta-1-D-thiopyranosato-S)gold(I) auranofin Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000334
-
-
Homo sapiens chloro(triphenylphosphine)gold(I)
0.018
-
-
Homo sapiens chloro(ethyldiphenylphosphine)gold(I)
0.1
-
-
Homo sapiens chloro(diethylphenylphosphine)gold(I)
0.25
-
-
Homo sapiens (triethylphosphine)gold(I) chloride