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Literature summary for 3.4.22.1 extracted from

  • Ramalho, S.D.; de Sousa, L.R.; Burger, M.C.; Lima, M.I.; da Silva, M.F.; Fernandes, J.B.; Vieira, P.C.
    Evaluation of flavonols and derivatives as human cathepsin B inhibitor (2015), Nat. Prod. Res., 29, 2212-2214 .
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme is involved in tumour progression and represents a potential therapeutic target in cancer Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
myricetin
-
Homo sapiens
quercetin
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P07858
-
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0049
-
pH and temperature not specified in the publication Homo sapiens myricetin
0.0082
-
pH and temperature not specified in the publication Homo sapiens quercetin

General Information

General Information Comment Organism
physiological function involved in tumour progression Homo sapiens