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Literature summary for 3.4.22.1 extracted from

  • Balboula, A.Z.; Yamanaka, K.; Sakatani, M.; Hegab, A.O.; Zaabel, S.M.; Takahashi, M.
    Cathepsin B activity is related to the quality of bovine cumulus oocyte complexes and its inhibition can improve their developmental competence (2010), Mol. Reprod. Dev., 77, 439-448.
    View publication on PubMed
Search for more literature for 3.4.22.1

Application

Application Comment Organism
biotechnology inhibition of cathepsin B greatly improves the developmental competence of bovine oocytes and increases the number of high-quality embryos Bos taurus
diagnostics cathepsin B activity can be a useful marker of oocyte quality Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
E-64 inhibition of cathepsin B greatly improves the developmental competence of bovine oocytes and increases the number of high-quality embryos, overview Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
 Bos taurus 5764
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
 Bos taurus
-
oocyte
-
 Bos taurus
-
ovarian cumulus cell
-
 Bos taurus
-

General Information

General Information Comment Organism
malfunction cathepsin B significantly decreases the number of apoptotic nuclei in both the cumulus cell layer of matured oocytes and blastocysts Bos taurus
additional information relation between cathepsin B activity and the quality of in vitro matured cumulus-oocyte complexes, IVM COCs, and denuded oocytes, overview Bos taurus