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Information on EC 1.2.1.24 - succinate-semialdehyde dehydrogenase (NAD+)

for references in articles please use BRENDA:EC1.2.1.24

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IUBMB Comments

This enzyme participates in the degradation of glutamate and 4-aminobutyrate. It is similar to EC 1.2.1.79 [succinate-semialdehyde dehydrogenase (NADP+)], and EC 1.2.1.16 [succinate-semialdehyde dehydrogenase (NAD(P)+)], but is specific for NAD+.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea

Synonyms
aldh5a1, aldh5a, aldehyde dehydrogenase 5a1, nad(+)-dependent succinic semialdehyde dehydrogenase, alphakgsa dehydrogenase, ssaldh, sso1629, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+
show the reaction diagram