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Search term: macrophage

<< < Results 101 - 200 of 465 > >>
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EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.13sterol esterase macrophage - 665963, 677459, 681075, 715834
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase macrophage - 666461, 711952, 743358
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.15protein-arginine deiminase macrophage - 666904, 711811
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage alveolar macrophage 667160, 686562
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.271GDP-L-fucose synthase macrophage - 667231
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.30fucose-1-phosphate guanylyltransferase macrophage - 667231
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.26prolyl oligopeptidase macrophage resident and elicited macrophage 667550
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B7matrix metalloproteinase-26 macrophage matrix metalloproteinase-26 is associated with macrophages and polymorphonuclear leukocytes 668149
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.56caspase-3 macrophage from arteriosclerotic carotid artery, presence of proapoptotic markers such as enzyme, poly(ADP-ribose) polymerase, apoptosis-inducing factor, c-Jun/AP-1, and proinflammatory markers such as macrophage migration inhibitory factor and cyclooxygenase-2. Colocalization of proapoptic markers and proinflammatory markers and oxidized low-density lipoproteins 668206
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage in inflamed temporal arteries 668868
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.27cathepsin S macrophage - 667984, 668394, 668898, 679696, 680995, 682236, 695946, 696630, 696638, 696641, 696743, 697361, 698859, 699142, 699442, 701151, 701183, 753968
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.65macrophage elastase macrophage - -, 668953, 671345, 683327, 708303, 708422, 754337, 754734, 754996
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.15cathepsin L macrophage the maturation of cathepsin L is impaired in bone marrow-derived macrophages infected with Mycobacterium avium or Mycobacterium tuberculosis 668959
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.41cathepsin F macrophage monocyte-derived cell culture, enzyme is secreted 669249
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.43cathepsin V macrophage in plaque areas of diseased blood vessels, cathepsin expression levels during differentiation, overview 669257
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B11ADAMTS1 endopeptidase macrophage - 669350, 755146
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage - -, 669503, 738833, 739113
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.35tissue kallikrein macrophage - 669519, 731671
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.63meprin B macrophage cortical and medullary macrophages of lymph node 669708
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B5matrix metalloproteinase-15 macrophage small expression 669713
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.533',5'-cyclic-AMP phosphodiesterase macrophage PDE4B. Ablation of PDE4B partially protects mice from LPS-induced shock 669723
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage activity occurs after differentiation of neutrophils to macrophages 669730
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage derived from bone-marrow, peritoneal macrophages, expression of isozyme 11beta-HSD1, not isozyme 11beta-HSD2 669730
Display the word mapDisplay the reaction diagram Show all sequences 5.6.1.3plus-end-directed kinesin ATPase macrophage - 670212
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.12carboxypeptidase M macrophage - 670291
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine and induced by dibutyryl cyclic adenosine 670294
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine, not inducible by dibutyryl cyclic adenosine 670294
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone-marrow derived 670356
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.20Carboxypeptidase U macrophage - 670940
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.2non-specific protein-tyrosine kinase macrophage - 490151, 671253, 672781, 675097, 691455, 692647
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.65macrophage elastase macrophage specific for 671345
Show all pathways known for 2.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 2.8.1.7cysteine desulfurase macrophage enzyme isoform Nfs1 671626
Show all pathways known for 2.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 2.8.1.7cysteine desulfurase macrophage mitochondrial isoform of Nfs1 671626
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage inducible enzyme 671728
Show all pathways known for 1.15.1.1Display the word mapDisplay the reaction diagram Show all sequences 1.15.1.1superoxide dismutase macrophage peritoneal macrophages exposed to He-Ne laser radiation. Changes in the activity of superoxide dismutase as well as the formation of nitric oxide and peroxynitrite depend to a large extent on the laser radiation dose. Activation of enzyme at low radiation doses is accompanied by nitric oxide level increase without changes in peroxynitrite. Enhanced laser radiation doses inhibit the enzyme 672292
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.31NAD+-protein-arginine ADP-ribosyltransferase macrophage - 672357
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.15beta-adrenergic-receptor kinase macrophage - -, 673187
Show all pathways known for 1.6.5.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.2NAD(P)H dehydrogenase (quinone) macrophage enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages 673798
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.16G-protein-coupled receptor kinase macrophage - 674691
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.137phosphatidylinositol 3-kinase macrophage the regulatory subunit p87PIKAP and the catalytic subunit p101 are both expressed 674783
Show all pathways known for 2.7.1.91Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.91sphingosine kinase macrophage - 674843
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.2non-specific protein-tyrosine kinase macrophage peritoneal and alveolar 675097
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.107diacylglycerol kinase (ATP) macrophage - 675157
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.2non-specific protein-tyrosine kinase macrophage peritoneal and splenic, and bone-marrow macrophages -, 675204
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage loss of ACAT activity in macrophages, either by pharmacological inhibition or by genetic knockout of ACAT-1, results in reduced induction of apoptosis in response to 7-ketocholesterol or oxidized low density lipoproteins. The apoptotic signal generated in macrophages by ACAT may be an arachidonyl oxysterol 675261
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B26proprotein convertase 5 macrophage - 675490
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage - 675057, 675686
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.51cruzipain macrophage studies are carried out using murine macrophage cell line J774 as well as bone marrow-derived macrophages from BALB/c mice 677418
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.3phospholipase C macrophage alveolar macrophage 677502
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.34cathepsin E macrophage - 677973, 679774
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.34cathepsin E macrophage mature form of CE in the endosomal structure 678531
Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.98histone deacetylase macrophage - 678911
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.3phospholipase C macrophage monocyte-derived macrophage, enzyme is activated by HIV-1 R5 gp120 interaction with CCR5 and is required for NF-kB-mediated chemokine CCL2 production triggered by R5 gp120 678920
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.79granzyme B macrophage - -, 679007, 731617, 754761
Display the word mapDisplay the reaction diagram Show all sequences 3.4.18.1cathepsin X macrophage tumor-associated 679023
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.1cathepsin B macrophage - 679023, 709347
Show all pathways known for 5.3.99.2Display the word mapDisplay the reaction diagram Show all sequences 5.3.99.2Prostaglandin-D synthase macrophage of gut mucosa 679038
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage - -, 679079, 681017, 681030, 697733, 698235, 700198, 700362, 700983, 708709, 708712, 717941, 718077
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage caspase-1-mediated macrophage necrosis is the source of the cytokine storm and rapid disease progression in anthrax lethal toxin-treated BALB/c mice 679097
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.82ADAMTS-4 endopeptidase macrophage - 677894, 679302
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2DNA topoisomerase (ATP-hydrolysing) macrophage - 679700
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.12sphingomyelin phosphodiesterase macrophage peritoneal 680143
Display the word mapDisplay the reaction diagram Show all sequences 3.4.19.3pyroglutamyl-peptidase I macrophage - 680172
Display the word mapDisplay the reaction diagram Show all sequences 3.4.15.1peptidyl-dipeptidase A macrophage mice with expression of angiotensin convertzing enzyme only in monocytes and macrophages have a marked resistance to the growth of melanoma due to an enhanced immune response 680175
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.5cathepsin D macrophage comparative transcriptome analysis is carried out in cholesterol-loaded monocyte-derived macrophages from low high density lipoprotein cholesterol (HDL-C) patients and control group: expression of CTSD is reduced by 50% in monocyte-derived macrophages of low HDL subjects, most significantly those with cholesterol efflux defects but without mutation in ABCA1 groups as compared with controls 680732
Show all pathways known for 3.1.4.4Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.4phospholipase D macrophage adhesion of primary neutrophils and monocyte-derived macrohages to fibronectin is accompanied by marked stimulation of enzyme activity. Similarly, adhesion of myeloid-macrophage cell lines to fibronectin, collagen, or plastic results in significant activation. Stimulation of enzyme is rapid and persists for at least 90 min 681193
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage IFN regulatory factor IRF-2(-/-) macrophages exhibit increased basal and gliotoxin-induced caspase-1 mRNA expression and enhanced caspase-1 activity 681202
Show all pathways known for 5.3.99.2Display the word mapDisplay the reaction diagram Show all sequences 5.3.99.2Prostaglandin-D synthase macrophage bone-marrow derived macrophage, lung and alveolar macrophage. Treatment with Escherichia coli lipopolysaccharide or Pseudomonas induce enzyme expression. Induction is regulated positively by AP-1 and negatively by p53 681206
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.34cathepsin E macrophage derived from mouse bone marrow precursors 681209
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage no significant modifications of pPAF-AH mRNA in macrophages or in ApoB100 values is observed in hepatitis C virus patients compared with controls 681670
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage the Gram-negative bacterium Shigella flexneri triggers pro-inflammatory apoptotic cell death in macrophages, which is crucial for the onset of an acute inflammatory diarrhoea termed bacillary dysentery. The Mxi-Spa type III secretion system promotes bacterial uptake and escape into the cytoplasm, where, dependent on the translocator/effector protein IpaB, caspase-1 and its substrate IL-1b are activated 681799
Show all pathways known for 3.1.2.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.2.2palmitoyl-CoA hydrolase macrophage up-regulated by lipopolysaccharide and that overexpression of Acot7 in a macrophage cell line alters the production of prostaglandins D2 and E2 682542
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone marrow derived. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Activation of caspase-1 by Bacillus anthracis lethal toxin requires binding, uptake, and endosome acidification to mediate translocation of lethal factor into the host cell cytosol. Catalytically active lethal factor cleaves cytosolic substrates and activates caspase-1 by a mechanism involving proteasome activity and potassium efflux. Lethal toxin activation of caspase-1 requires the inflammasome adapter Nalp1. Salmonella infection activates caspase-1 through an independent pathway requiring the inflammasome adapter Ipaf. These distinct mechanisms of caspase-1 activation converge on a common pathway of caspase-1-dependent cell death featuring DNA cleavage, cytokine activation, and, ultimately, cell lysis resulting from the formation of membrane pores between 1.1 and 2.4 nm in diameter and pathological ion fluxes that can be blocked by glycine 682588
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.52beta-N-acetylhexosaminidase macrophage the importance of beta-hexosaminidase for restricting mycobacterial growth during mammalian infections is confirmed in macrophages from beta-hexosaminidase knockout mice. beta-Hexosaminidase is characterized as a peptidoglycan hydrolase that exerts its mycobactericidal effect at the macrophage plasma membrane during mycobacteria-induced secretion of lysosomes 682592
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.25mitogen-activated protein kinase kinase kinase macrophage TPL-2 and MEKK1 682954
Show all pathways known for 3.2.2.5Display the word mapDisplay the reaction diagram Show all sequences 3.2.2.5NAD+ glycohydrolase macrophage from bone marrow. Tumor necrosis factor alpha upregulates CD38. Induced CD38 expression enhances inflammatory gene expression by decreasing ERK1/2 phosphorylation and increasing NF kappaB activation. It negatively affects the expression of osteoclast markers. CD38 may reduce osteoclastogenesis and increase inflammatory gene induction by decreasing cellular histone deacetylase activity 683052
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.65macrophage elastase macrophage alveolar -, 683054, 708452, 709559, 752886
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.6coagulation factor Xa macrophage high expression level in bronchoalveolar lavage fluid macrophages from asthmatic mice 683057
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.41cathepsin F macrophage derived from cultured monocytes 683112
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34Legumain macrophage M-CSF differentiated primary macrophages, in vitro expression, also detected in the culture media 683113
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.34Legumain macrophage of atherosclerotic aorta of aging Apolipoprotein E deficient mice, mRNA expression increases with development of atherosclerosis 683113
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.23matrilysin macrophage - 683356
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.71endothelin-converting enzyme 1 macrophage from blood, determination of enzyme expression by immunohistochemical analysis using a combination of ECE-1 isoform-specific antibodies, expression of isozymes ECE-1a and ECE-1c 683440
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.109matriptase macrophage - 683489, 695463, 698077
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B macrophage secretion of MMP-9 in the early phase of peritonitis, no MMP-9 production in unstimulated macrophages -, 683525
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.73u-Plasminogen activator macrophage - -, 683623, 683741, 707951
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.73u-Plasminogen activator macrophage from bone-marrow 683623
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.22metallocarboxypeptidase D macrophage - 683703
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B macrophage activated, MMP-9 secretion -, 683733
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B macrophage secretion of MMP-9, transcription factor NF-kappaB is important in MMP gene regulation in macrophage cells 683749
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.65macrophage elastase macrophage MMP-12 is secreted by macrophages at sites of inflammation 683781
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B macrophage - -, 684007, 707043, 708724, 709413, 709572, 709950, 733303, 733959
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage peritoneal -, 684350
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage - 684384, 688998, 689301
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.7plasmin macrophage plasmin triggers expression and release of proinflammatory cytokines such as TNF-alpha and IL-6 in human monocyte-derived macrophages with a somewhat lower potency than the standard stimulus lipopolysaccharide. Plasmin-induced activation of JAK1, p38, ERK1/2, and NF-kappaB is indispensable for the cytokine expression 684778
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage monocyte-derived macrophage 684780
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B1hyaluronan-binding serine protease macrophage highly expressed in macrophages of atherosclerotic lesions 684801
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage peritoneal -, 684803
Display the reaction diagram Show all sequences 2.7.7.96ADP-D-ribose pyrophosphorylase macrophage - 684834
Show all pathways known for 1.15.1.1Display the word mapDisplay the reaction diagram Show all sequences 1.15.1.1superoxide dismutase macrophage - 685864
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