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Literature summary for 3.4.21.6 extracted from

  • Shinagawa, K.; Martin, J.A.; Ploplis, V.A.; Castellino, F.J.
    Coagulation factor Xa modulates airway remodeling in a murine model of asthma (2007), Am. J. Respir. Crit. Care Med., 175, 136-143.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.6

Inhibitors

Inhibitors Comment Organism Structure
tick anticoagulant peptide TAP Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus effects of factor X on the respiratory function and asthmatic response in mice, factor X transcript levels and factor Xa activity are increased in lungs of asthmatic mice leading to a significant decrease in the thickness of the mucosal layer and in lung collagen deposition, factor Xa modulates airway remodeling, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
lung murine model of ovalbumin-induced asthma, factor X transcript levels and factor Xa activity are increased in lungs of asthmatic mice Mus musculus
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macrophage high expression level in bronchoalveolar lavage fluid macrophages from asthmatic mice Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information effects of factor X on the respiratory function and asthmatic response in mice, factor X transcript levels and factor Xa activity are increased in lungs of asthmatic mice leading to a significant decrease in the thickness of the mucosal layer and in lung collagen deposition, factor Xa modulates airway remodeling, overview Mus musculus ?
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 ?
S2222 + H2O a chromogenic substrate Mus musculus ?
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 ?

Synonyms

Synonyms Comment Organism
factor Xa
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 Mus musculus
procoagulant factor X
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 Mus musculus