Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.6.1.3 extracted from

  • Kopp, P.; Lammers, R.; Aepfelbacher, M.; Woehlke, G.; Rudel, T.; Machuy, N.; Steffen, W.; Linder, S.
    The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages (2006), Mol. Biol. Cell, 17, 2811-2823.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.6.1.3

Localization

Localization Comment Organism GeneOntology No. Textmining
podosome KIF1C is enriched at a subset of microtubule plus ends, that contact podosomes Homo sapiens 2102
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Homo sapiens plus-end-enriched motor that targets regions of podosome turnover. Kinesin KIF1C is a central player in the microtubule-dependent regulation of podosomes. The KIF1C-myosin IIA interface may play a role in facilitating podosomes dynamics in a subcellular fine-tuned manner ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
macrophage
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n plus-end-enriched motor that targets regions of podosome turnover. Kinesin KIF1C is a central player in the microtubule-dependent regulation of podosomes. The KIF1C-myosin IIA interface may play a role in facilitating podosomes dynamics in a subcellular fine-tuned manner Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n plus-end-enriched motor that targets regions of podosome turnover Homo sapiens ADP + phosphate + a kinesin associated with a microtubule at position n+1 (toward the plus end)
-
 ?

Synonyms

Synonyms Comment Organism
kinesin KIF1C member of the kinesin-3 family Homo sapiens