Application | Comment | Organism |
---|---|---|
medicine | studies on a functional role of legumain in atherogenesis | Homo sapiens |
medicine | studies on a functional role of legumain in atherogenesis | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q99538 | - |
- |
Homo sapiens | Q99538 | Homo sapiens | - |
Mus musculus | O89017 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | lesions at the aortic sinus and in injured carotid arteries of Apolipoprotein E deficient mice, mRNA expression increases with development of atherosclerosis in the aorta | Mus musculus | - |
corona | inflamed areas in advanced human coronary atherosclerotic plaques | Homo sapiens | - |
HUVEC cell | human umbilical vascular endothelial cells (HUVECs) tested in migration/proliferation and invasion assays | Homo sapiens | - |
macrophage | M-CSF differentiated primary macrophages, in vitro expression, also detected in the culture media | Homo sapiens | - |
macrophage | of atherosclerotic aorta of aging Apolipoprotein E deficient mice, mRNA expression increases with development of atherosclerosis | Mus musculus | - |
monocyte | fluorimetric assay measuring legumain protease activity applied | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
expression determined by RT-PCR, in situ hybridization and immunohistochemical analysis, role of legumain in the pathophysiology of atherosclerosis analyzed | Mus musculus |
additional information | - |
expression in atherosclerotic tissues determined by RT-PCR, in situ hybridization and immunohistochemical analysis, role of legumain in the pathophysiology of atherosclerosis analyzed | Homo sapiens |
additional information | - |
expression in atherosclerotic tissues determined by RT-PCR, in situ hybridization and immunohistochemical analysis, role of legumain in the pathophysiology of atherosclerosis analyzed | Mus musculus |
additional information | - |
expression in atherosclerotic tissues determined by RT-PCR, in situ hybridization and immunohistochemical analysis, role of legumain in the pathophysiology of atherosclerosis analyzed, human monocyte legumain activity assay described, migration/proliferation and invasion assay described | Homo sapiens |
additional information | - |
role of legumain in the pathophysiology of atherosclerosis analyzed, human monocyte legumain activity assay described, migration/proliferation and invasion assay described | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
AEP | - |
Homo sapiens |
AEP | - |
Mus musculus |
asparagine endopeptidase | - |
Homo sapiens |
asparagine endopeptidase | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
37 | - |
activity assay at | Mus musculus |