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2-aminobenzoyl-MISLMKRPPGFSPFRSS(PO3H2)RI-NH2 + H2O
2-aminobenzoyl-MISLM + KRPPGFSPFRSS(PO3H2)RI-NH2
-
-
-
-
?
2-aminobenzoyl-MISLMKRPPGFSPFRSSRI-NH2 + H2O
2-aminobenzoyl-MISLM + KRPPGFSPFRSSRI-NH2
-
-
-
-
?
2-aminobenzoyl-TSVIRRVQ-ethylenediamine + H2O
?
-
-
-
-
?
Abz-ALFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-FLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-FRSSR-Q-EDDnp + H2O
Abz-FR + SSR-Q-EDDnp
-
-
-
?
Abz-GFSPFRSLRI-Q-EDDnp + H2O
Abz-GFSPFR + SLRI-Q-EDDnp
-
-
-
?
Abz-GFSPFRSSRI-Q-EDDnp + H2O
Abz-GFSPFR + SSRI-Q-EDDnp
-
-
-
?
Abz-GLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-HLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-ILFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KAFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KFFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KLFFSK-EDDnp + H2O
Abz-KLF + FSK-EDDnp
-
-
-
-
?
Abz-KLFRSK-EDDnp + H2O
Abz-KLF + RSK-EDDnp
-
-
-
-
?
Abz-KLFSAKQ-EDDnp + H2O
Abz-KLF + SAKQ-EDDnp
-
-
-
-
?
Abz-KLFSGKQ-EDDnp + H2O
Abz-KLF + SGKQ-EDDnp
-
-
-
-
?
Abz-KLFSIKQ-EDDnp + H2O
Abz-KLF + SIKQ-EDDnp
-
-
-
-
?
Abz-KLFSLKQ-EDDnp + H2O
Abz-KLF + SLKQ-EDDnp
-
-
-
-
?
Abz-KLFSNKQ-EDDnp + H2O
Abz-KLF + SNKQ-EDDnp
-
-
-
-
?
Abz-KLFSRKQ-EDDnp + H2O
Abz-KLF + SRKQ-EDDnp
-
-
-
-
?
Abz-KLFSSDQ-EDDnp + H2O
Abz-KLF + SSDQ-EDDnp
-
-
-
-
?
Abz-KLFSSEQ-EDDnp + H2O
Abz-KLF + SSEQ-EDDnp
-
-
-
-
?
Abz-KLFSSGQ-EDDnp + H2O
Abz-KLF + SSGQ-EDDnp
-
-
-
-
?
Abz-KLFSSIQ-EDDnp + H2O
Abz-KLF + SSIQ-EDDnp
-
-
-
-
?
Abz-KLFSSK-EDDnp + H2O
Abz-KLF + SSK-EDDnp
-
-
-
-
?
Abz-KLFSSKQ-EDDnp + H2O
Abz-KLF + SSKQ-EDDnp
-
-
-
-
?
Abz-KLFSSLQ-EDDnp + H2O
Abz-KLF + SSLQ-EDDnp
-
-
-
-
?
Abz-KLFSSNQ-EDDnp + H2O
Abz-KLF + SSNQ-EDDnp
-
-
-
-
?
Abz-KLFSSQQ-EDDnp + H2O
Abz-KLF + SSQQ-EDDnp
-
-
-
-
?
Abz-KLFSSRQ-EDDnp + H2O
Abz-KLF + SSRQ-EDDnp
-
-
-
-
?
Abz-KLFSSSQ-EDDnp + H2O
Abz-KLF + SSSQ-EDDnp
-
-
-
-
?
Abz-KLFSSVQ-EDDnp + H2O
Abz-KLF + SSVQ-EDDnp
-
-
-
-
?
Abz-KLFSVKQ-EDDnp + H2O
Abz-KLF + SVKQ-EDDnp
-
-
-
-
?
Abz-KLFTSK-EDDnp + H2O
Abz-KLF + TSK-EDDnp
-
-
-
-
?
Abz-KLFWSK-EDDnp + H2O
Abz-KLF + WSK-EDDnp
-
-
-
-
?
Abz-KLRSSQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KLYSSK-EDDnp + H2O
?
-
-
-
-
?
Abz-KPFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KVFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-KYFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-LLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-MISLMKLP-Q-EDDnp + H2O
Abz-MISLM + KLP-Q-EDDnp
-
-
-
?
Abz-MISLMKRP-Q-EDDnp + H2O
Abz-MISLM + KRP-Q-EDDnp
-
-
-
?
Abz-MISLMKRPPGFSPFRSSRI-NH2 + H2O
Abz-MISLM + KRPPGFSPF + RSSRI-NH2
-
-
-
-
?
Abz-NLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-NLYRVE-Q-EDDnp + H2O
Abz-NLY + RVE-Q-EDDnp
-
-
-
-
?
Abz-QLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-RLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Abz-VLFSSKQ-EDDnp + H2O
?
-
-
-
-
?
Ac-GKAFRR-L12ADT + H2O
?
-
peptide coupled to cytotoxin thapsigarin, L12ADT, as an enzyme-activated prodrug. Enzyme cleaves at R-residue adjacent to L12ADT
-
-
?
acetyl-2-aminohexanoic acid-Arg methyl ester + H2O
acetyl-2-aminohexanoic acid-Arg + methanol
-
-
-
-
?
acetyl-Ala-Arg methyl ester + H2O
acetyl-Ala-Arg + methanol
-
-
-
-
?
acetyl-Ala-Arg-Ala + H2O
acetyl-Ala-Arg + L-alanine
-
-
-
-
?
acetyl-Ala-Arg-Arg methyl ester + H2O
?
-
-
-
-
?
acetyl-Ala-Leu-Arg-p-nitroanilide + H2O
acetyl-Ala-Leu-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Ala-Phe-Arg methyl ester + H2O
acetyl-Ala-Phe-Arg + methanol
-
-
-
-
?
acetyl-Ala-Phe-Arg-Ala + H2O
acetyl-Ala-Phe-Arg + L-alanine
-
-
-
-
?
acetyl-Ala-Phe-Arg-Ala-NH2 + H2O
acetyl-Ala-Phe-Arg + Ala-NH2
-
-
-
-
?
acetyl-Ala-Phe-Arg-p-nitroanilide + H2O
acetyl-Ala-Phe-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Ala-Thr-Arg-p-nitroanilide + H2O
acetyl-Ala-Thr-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Arg methyl ester + H2O
acetyl-Arg + methanol
-
-
-
-
?
acetyl-Arg-Ala-NH2 + H2O
acetyl-Arg + Ala-NH2
-
-
-
-
?
acetyl-Arg-p-nitroanilide + H2O
acetyl-Arg + p-nitroaniline
-
-
-
-
?
acetyl-D-Ala-Arg methyl ester + H2O
acetyl-D-Ala-Arg + methanol
-
-
-
-
?
acetyl-D-Phe-Arg methyl ester + H2O
acetyl-D-Phe-Arg + methanol
-
-
-
-
?
acetyl-Glu-Leu-Arg-p-nitroanilide + H2O
acetyl-Glu-Leu-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Glu-Lys-Arg-p-nitroanilide + H2O
acetyl-Glu-Lys-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Glu-Phe-Arg-p-nitroanilide + H2O
acetyl-Glu-Phe-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Glu-Thr-Arg-p-nitroanilide + H2O
acetyl-Glu-Thr-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Gly-Arg methyl ester + H2O
acetyl-Gly-Arg + methanol
-
-
-
-
?
acetyl-Gly-Arg-Ser-Val-Gln + H2O
acetyl-Gly-Arg + Ser-Val-Gln
-
-
-
?
acetyl-Ile-Arg methyl ester + H2O
acetyl-Ile-Arg + methanol
-
-
-
-
?
acetyl-Leu-Arg methyl ester + H2O
acetyl-Leu-Arg + methanol
-
-
-
-
?
acetyl-Met-Arg methyl ester + H2O
acetyl-Met-Arg + methanol
-
-
-
-
?
acetyl-Phe-Arg ethyl ester + H2O
acetyl-Phe-Arg + ethanol
-
-
-
-
?
acetyl-Phe-Arg methyl ester + H2O
acetyl-Phe-Arg + methanol
acetyl-Phe-Arg-Ala + H2O
acetyl-Phe-Arg + L-alanine
-
-
-
-
?
acetyl-Phe-Arg-p-nitroanilide + H2O
acetyl-Phe-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Phe-Arg-Ser-NH2 + H2O
acetyl-Phe-Arg + Ser-NH2
-
-
-
?
acetyl-Phe-Arg-Ser-Val-Gln + H2O
acetyl-Phe-Arg + Ser-Val-Gln
-
-
-
?
acetyl-Phe-Arg-Ser-Val-NH2 + H2O
acetyl-Phe-Arg + Ser-Val-NH2
-
-
-
?
acetyl-Pro-Arg methyl ester + H2O
acetyl-Pro-Arg + methanol
-
-
-
-
?
acetyl-Pro-Phe-Arg methyl ester + H2O
acetyl-Pro-Phe-Arg + methanol
-
-
-
-
?
acetyl-Pro-Phe-Arg-Ala + H2O
acetyl-Pro-Phe-Arg + L-alanine
-
-
-
-
?
acetyl-Pro-Phe-Arg-Ala-NH2 + H2O
acetyl-Pro-Phe-Arg + Ala-NH2
-
-
-
-
?
acetyl-Pro-Phe-Arg-p-nitroanilide + H2O
acetyl-Pro-Phe-Arg + p-nitroaniline
-
-
-
-
?
acetyl-Trp-2-aminohexanoic acid methyl ester + H2O
?
-
-
-
-
?
acetyl-Trp-Arg methyl ester + H2O
acetyl-Trp-Arg + methanol
-
-
-
-
?
acetyl-Tyr-Arg methyl ester + H2O
acetyl-Tyr-Arg + methanol
-
-
-
-
?
acetyl-Val-Arg methyl ester + H2O
acetyl-Val-Arg + methanol
-
-
-
-
?
Ala-Ala-Arg-7-amido-4-methylcoumarin + H2O
Ala-Ala-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
Ala-Arg-Arg-7-amido-4-methylcoumarin + H2O
Ala-Arg-Arg + 7-amino-4-methylcoumarin
angiotensin I + H2O
?
-
reaction with prostate enzyme, very low reaction with submandibular enzyme
-
-
?
angiotensinogen + H2O
?
-
reaction with prostate enzyme, no reaction with submandibular enzyme
-
-
?
angiotensinogen + H2O
angiotensin
-
-
-
?
benzoyl-Phe-Val-Arg-7-amido-4-methylcoumarin + H2O
benzoyl-Phe-Val-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzoyl-Pro-Phe-Arg-p-nitroanilide + H2O
benzoyl-Pro-Phe-Arg + p-nitroaniline
-
-
-
-
?
benzyloxycarbonyl-Arg methyl ester + H2O
benzyloxycarbonyl-Arg + methanol
benzyloxycarbonyl-Arg-Ala-NH2 + H2O
benzyloxycarbonyl-Arg + Ala-NH2
-
-
-
-
?
benzyloxycarbonyl-Arg-p-nitroanilide + H2O
benzyloxycarbonyl-Arg + p-nitroaniline
-
-
-
-
?
Benzyloxycarbonyl-Lys methyl ester + H2O
Benzyloxycarbonyl-Lys + methanol
-
-
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
?
-
about 30% of the activity with Pro-Phe-Arg-4-methylcoumarin 7-amide
-
-
?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Phe-Ser-Arg-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-Phe-Ser-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
benzyloxycarbonyl-Pro-Gly-Arg methyl ester + H2O
benzyloxycarbonyl-Pro-Gly-Arg + methanol
-
-
-
-
?
benzyloxycarbonyl-Pro-Phe-Arg methyl ester + H2O
benzyloxycarbonyl-Pro-Phe-Arg + methanol
-
-
-
-
?
benzyloxycarbonyl-Tyr-4-nitrophenyl ester + H2O
benzyloxycarbonyl-Tyr + 4-nitrophenol
-
-
-
-
?
citrated bovine plasma + H2O
?
-
-
-
-
?
citrated dog plasma + H2O
?
-
-
-
-
?
D-Ile-Pro-Arg-4-nitroanilide + H2O
D-Ile-Pro-Arg + 4-nitroaniline
-
weak activity
-
-
?
D-Pro-Phe-Arg-4-methylcoumarin-7-amide + H2O
?
D-Pro-Phe-Arg-4-nitroanilide + H2O
D-Pro-Phe-Arg + 4-nitroaniline
-
weak activity
-
-
?
D-Pro-Phe-Phe-4-methylcoumarin-7-amide + H2O
?
D-Pro-Phe-Phe-7-amido4-methylcoumarin + H2O
D-Pro-Phe-Phe + 7-amino-4-methylcoumarin
-
-
-
-
?
D-Val-Leu-Arg-4-nitroanilide + H2O
D-Val-Leu-Arg + 4-nitroaniline
D-Val-Leu-Arg-7-amido-4-trifluoromethylcoumarin + H2O
D-Val-Leu-Arg + 7-amino-4-trifluoromethylcoumarin
-
-
-
-
?
D-Val-Leu-Arg-p-nitroanilide + H2O
D-Val-Leu-Arg + p-nitroaniline
D-Val-Leu-Lys-4-nitroanilide + H2O
D-Val-Leu-Lys + 4-nitroaniline
DL-Val-Leu-Arg-p-nitroanilide + H2O
DL-Val-Leu-Arg + p-nitroaniline
epithelial sodium channel + H2O
activated epithelial sodium channel + ?
-
-
-
-
?
FSPFRSVQ + H2O
FSPFR + SVQ
-
-
-
?
Gelatin + H2O
?
-
-
-
-
?
Gln-Ala-Arg-7-amido-4-methylcoumarin + H2O
Gln-Ala-Arg + 7-amino-4-methylcoumarin
-
-
-
?
Gly-Pro-Arg-7-amido-4-methylcoumarin + H2O
Gly-Pro-Arg + 7-amino-4-methylcoumarin
-
-
-
?
H-D-Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O
H-D-Pro-Phe-Arg + 7-amino-4-methylcoumarin
-
i.e. S-2302
-
-
?
human high molecular weight kininogen + H2O
?
-
-
-
-
?
insulin-like growth factor binding protein + H2O
?
-
-
-
-
?
insulin-like growth factor binding proteins
?
insulin-like growth factor binding proteins
insulin-like growth factor binding protein fragments
kinin B2 receptor + H2O
?
-
tissue kallikrein directly activates kinin B2 receptor in the absence of kininogen
-
-
?
kininogen + H2O
bradykinin + ?
-
-
-
-
?
kininogen + H2O
bradykinin + kinin
kininogen + H2O
bradykinin + kinin heavy chain + kinin light chain
kininogen + H2O
kallidin + kinin heavy chain + kinin light chain
kininogen + H2O
kinin + ?
kininogen + H2O
kinin + bradykinin
-
-
-
-
?
L-Pro-L-Phe-L-Arg-7-amido-4-methylcoumarin + H2O
L-Pro-L-Phe-L-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
Laminin + H2O
?
-
-
-
-
?
Leu-Leu-Arg-7-amido-4-methylcoumarin + H2O
Leu-Leu-Arg + 7-amino-4-methylcoumarin
-
-
-
-
?
low density lipoprotein + H2O
?
-
-
-
?
low molecular weight kininogen + H2O
3.4.21.35 tissue kallikrein
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