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Information on EC - tissue kallikrein

for references in articles please use BRENDA:EC3.4.21.35
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
       tissue kallikrein
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Reaction Schemes
Preferential cleavage of Arg-/- bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-/- or Leu-/-. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-/- bonds
bradykininogenase, callicrein, depot-Padutin, dilminal D, EC, EC, EMSP1, GK1, glandular kallikrein, glandular kallikrein 2, more