Literature summary for 3.4.24.B5 extracted from

Toft-Hansen, H.; Nuttall, R.K.; Edwards, D.R.; Owens, T.
Key metalloproteinases are expressed by specific cell types in experimental autoimmune encephalomyelitis (2004), J. Immunol., 173, 5209-5218.

Search for more literature for 3.4.24.B5

Application

Application	Comment	Organism
medicine	MMP-15 is downregulated in experimental autoimmune encephalomyelitis, expression of MMP-15 correlates with disease course	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Mus musculus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	female SJL/J mice and mice with adoptively transferred myelin basic protein-specific experimental autoimmune encephalomyelitis	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	trends in expression of MMP-15 is similar between brain and spinal cord samples	Mus musculus	-
macrophage	small expression	Mus musculus	-
marrow cell	MMP-15 is expressed at a significantly higher level by myeloid cells than by T cells	Mus musculus	-
microglia	MMP-15 is mainly expressed by resting microglia, and this is reduced 15fold in experimental autoimmune encephalomyelitis	Mus musculus	-
additional information	T-cell	Mus musculus	-
spinal cord	MMP-15 message is down-regulated 5.5fold in experimental autoimmune encephalomyelitis	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
MMP-15	-	Mus musculus

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Release 2023.1 (January 2023)