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Information on EC 2.7.11.16 - G-protein-coupled receptor kinase

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IUBMB Comments
Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.15, beta-adrenergic-receptor kinase).
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
g-protein-coupled receptor kinase, g protein-coupled receptor kinase 5, g protein-coupled receptor kinase 4, g protein-coupled receptor kinase 6, grk4gamma, g-protein-coupled receptor kinase 5, g-protein-coupled receptor kinase 6, g-protein coupled receptor kinase 5, grk-6, g protein-coupled receptor kinase grk6, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + [G protein-coupled receptor] = ADP + [G protein-coupled receptor]phosphate
show the reaction diagram
ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate
show the reaction diagram
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