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Information on EC 3.4.17.20 - Carboxypeptidase U

for references in articles please use BRENDA:EC3.4.17.20

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IUBMB Comments

Pro-carboxypeptidase U in (human) plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U, with activity similar to that of the more stable lysine carboxypeptidase, except that no preference is shown for Lys over Arg. A zinc enzyme, In peptidase family M14 (carboxypeptidase A family)

The enzyme appears in viruses and cellular organisms

Synonyms
tafia, thrombin-activatable fibrinolysis inhibitor, thrombin activatable fibrinolysis inhibitor, procpu, procarboxypeptidase b, carboxypeptidase u, thrombin-activable fibrinolysis inhibitor, procarboxypeptidase u, carboxypeptidase b2, plasma carboxypeptidase b, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
release of C-terminal Arg and Lys from a polypeptide
show the reaction diagram