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Literature summary for 3.4.18.1 extracted from

  • Vasiljeva, O.; Papazoglou, A.; Krueger, A.; Brodoefel, H.; Korovin, M.; Deussing, J.; Augustin, N.; Nielsen, B.S.; Almholt, K.; Bogyo, M.; Peters, C.; Reinheckel, T.
    Tumor cell-derived and macrophage-derived cathepsin B promotes progression and lung metastasis of mammary cancer (2006), Cancer Res., 66, 5242-5250.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information cell surface cathepsin X compensates for CTSB in PyMT,ctsb-/- tumor cells, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
-
Mus musculus 9986
-
lysosome
-
Mus musculus 5764
-
plasma membrane
-
Mus musculus 5886
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
wild-type and CTSB-deficient female and male mice
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Mus musculus
-
macrophage tumor-associated Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin-7-amide + H2O
-
Mus musculus benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
cathepsin X
-
Mus musculus