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Literature summary for 3.4.23.34 extracted from

  • Zaidi, N.; Herrmann, T.; Voelter, W.; Kalbacher, H.
    Recombinant cathepsin E has no proteolytic activity at neutral pH (2007), Biochem. Biophys. Res. Commun., 360, 51-55.
    View publication on PubMed
Search for more literature for 3.4.23.34

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome CatE is normally most acitve at acidic pH, which corresponds to the active endosomal form Mus musculus 5768
-
Golgi apparatus
-
 Mus musculus 5794
-
intracellular
-
 Mus musculus 5622
-
plasma membrane
-
 Mus musculus 5886
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
dendritic cell
-
 Mus musculus
-
gastric epithelial cell
-
 Mus musculus
-
gastric mucosa
-
 Mus musculus
-
glial cell of aged rats Mus musculus
-
lymphocyte
-
 Mus musculus
-
macrophage
-
 Mus musculus
-
microglia
-
 Mus musculus
-
neuron of aged rats Mus musculus
-
pancreatic ductal adenocarcinoma cell
-
 Mus musculus
-
pancreatic juice
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dynorphin A + H2O no cleavage at pH 7.4 Mus musculus hydrolyzed dynorphin A
-
 ?
glucagon + ATP + H2O is digested at pH 4.0 but not at pH 7.4 Mus musculus hydrolyzed glucagon + ?
-
 ?
neurotensin + H2O no cleavage at pH 7.4 Mus musculus hydrolyzed neurotensin
-
 ?

Synonyms

Synonyms Comment Organism
CatE
-
 Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4
-
 no cleavage at neutral pH as reported in earlier studies, only cleavage at acidic pH Mus musculus

pH Range

pH Minimum pH Maximum Comment Organism
additional information
-
 CatE is normally most acitve at acidic pH, which corresponds to the active endosomal form Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus