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Literature summary for 3.4.23.34 extracted from

  • Kakehashi, H.; Nishioku, T.; Tsukuba, T.; Kadowaki, T.; Nakamura, S.; Yamamoto, K.
    Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E (2007), J. Immunol., 179, 5728-5737.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
endosome cathepsin E is localized in endosomal structures of antigen-presenting cells Mus musculus 5768
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
culture condition:antigen-presenting cell
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Mus musculus
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dendritic cell
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Mus musculus
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macrophage derived from mouse bone marrow precursors Mus musculus
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peritoneal macrophage
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Mus musculus
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pH Range

pH Minimum pH Maximum Comment Organism
additional information
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lysosomal pH of the wild-type macrophage estimated to 5.3 to 5.5, lysosomal pH of catE-deficient macrophage raises to 6.4 to 6.5 Mus musculus