Ontology explorer

BTO (BRENDA Tissue Ontology)

Download as: OBO OWL

Change ontology: Version 2021-10-23

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Tissue

Details for macrophage

macrophage

BTO (BRENDA Tissue Ontology) ID

BTO:0000801

BTO:0000801 is linked to 268 enzymes:

Definition

Relatively long-lived phagocytic cell of mammalian tissues, derived from blood monocyte. Macrophages from different sites have distinctly different properties. Main types are peritoneal and alveolar macrophages, tissue macrophages (histiocytes), Kupffer cells of the liver, and osteoclasts. In response to foreign materials may become stimulated or activated. Macrophages play an important role in killing of some bacteria, protozoa, and tumour cells, release substances that stimulate other cells of the immune system, and are involved in antigen presentation. May further differentiate within chronic inflammatory lesions to epithelioid cells or may fuse to form foreign body giant cells or Langhans giant cells

Synonyms

1. macrophagocyte
2. monocyte-derived macrophage

References

1. The Dictionary of Cell and Molecular Biology: Third Edition

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Tree view

tissues, cell types and enzyme sources

tissues, cell types and enzyme sources is a

animal

whole body is a

body wall

cardiovascular system part of

connective tissue part of

embryonic structure is a

gland

head

hematopoietic system part of

blood

arterial blood is a

blast cell part of

hematopoietic stem cell derives from

immune stem cell derives from

leukemic stem cell derives from

lymphoid progenitor cell derives from

myeloid progenitor cell derives from

marrow cell derives from

erythroblast is a

megakaryocyte is a

mononuclear phagocyte is a

monocyte

macrophage derives from

premonocyte is a

myeloid cell line derives from

normoblast is a

polymorphonuclear leukocyte is a

promyelocyte is a

blood clot derives from

blood plasma part of

granuloma cell

hematopoietic cell part of

peripheral blood part of

venous blood is a

hemolymph

hemolymph vessel part of

lymph

lymph vessel part of

lymphoid tissue part of

reticuloendothelial system part of

serum

immune system part of

integument part of

limb

muscular system part of

nervous system part of

pacemaker cell part of

pluripotent stem cell part of

primary cell part of

respiratory system part of

sense organ part of

skeletal system part of

soft body part part of

trunk

urogenital system part of

viscus

fungus

organism form is a

other source is a

plant