EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.7.11.1 | non-specific serine/threonine protein kinase |
macrophage |
- |
742344 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
macrophage |
isoforms NOX2 and NOX4 |
742567 |
1.13.11.33 | arachidonate 15-lipoxygenase |
macrophage |
alveolar |
742613 |
1.13.11.33 | arachidonate 15-lipoxygenase |
macrophage |
high level expression in peritoneal macrophages, while murine peripheral monocytes, alveolar macrophages and bone marrow-derived macrophages express alox15 only at low levels |
742613 |
7.1.1.2 | NADH:ubiquinone reductase (H+-translocating) |
macrophage |
- |
742878 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
macrophage |
- |
742310, 743287 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
macrophage |
- |
743358 |
1.2.1.36 | retinal dehydrogenase |
macrophage |
hepatic |
743375 |
3.2.1.207 | mannosyl-oligosaccharide alpha-1,3-glucosidase |
macrophage |
- |
743920 |
7.2.1.3 | ascorbate ferrireductase (transmembrane) |
macrophage |
- |
744757 |
1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
macrophage |
- |
745510 |
6.1.1.6 | lysine-tRNA ligase |
macrophage |
- |
745539 |
6.1.1.15 | proline-tRNA ligase |
macrophage |
- |
-, 745867 |
6.1.1.17 | glutamate-tRNA ligase |
macrophage |
- |
-, 745867 |
6.1.1.2 | tryptophan-tRNA ligase |
macrophage |
- |
-, 745868 |
1.14.16.5 | alkylglycerol monooxygenase |
macrophage |
- |
746303 |
4.1.1.17 | ornithine decarboxylase |
macrophage |
M1 and M2 macrophages |
747449 |
4.1.1.17 | ornithine decarboxylase |
macrophage |
M1 and M2 macrophages, human colonic macrophages express increased ODC levels in active ulcerative colitis and Crohn's disease, colitis-associated dysplasia, and colitis-associated carcinogenesis |
747449 |
5.3.99.2 | Prostaglandin-D synthase |
macrophage |
- |
747984 |
4.1.1.17 | ornithine decarboxylase |
macrophage |
bone-marrow-derived macrophages |
749189 |
3.1.4.11 | phosphoinositide phospholipase C |
macrophage |
M1, M2 and unpolarized M0 macrophages |
751177 |
3.1.1.23 | acylglycerol lipase |
macrophage |
- |
751669 |
3.1.5.B1 | dNTPase |
macrophage |
- |
752156 |
3.4.22.B74 | SENP6 peptidase |
macrophage |
- |
752453 |
3.4.21.53 | Endopeptidase La |
macrophage |
- |
752805 |
3.4.21.69 | Protein C (activated) |
macrophage |
- |
752736, 753066 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
macrophage |
expressed in macrophages in response to bacterial products and inflammatory cytokines |
753165 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
macrophage |
- |
753191 |
3.1.1.111 | phosphatidylserine sn-1 acylhydrolase |
macrophage |
THP-1-derived macrophage |
753210 |
3.3.2.6 | leukotriene-A4 hydrolase |
macrophage |
- |
753500 |
3.4.24.63 | meprin B |
macrophage |
bone marrow-derived |
-, 753536 |
3.3.2.9 | microsomal epoxide hydrolase |
macrophage |
alveolar |
753726 |
3.4.24.22 | stromelysin 2 |
macrophage |
bone marrow-derived and alveolar |
753928 |
3.4.22.27 | cathepsin S |
macrophage |
cathepsin S is expressed by macrophages infiltrating the human kidney |
753981 |
3.4.22.59 | caspase-6 |
macrophage |
- |
754137 |
3.4.22.B26 | calpain 6 |
macrophage |
- |
754258 |
3.4.24.22 | stromelysin 2 |
macrophage |
isolated resident alveolar and bone marrow-derived macrophages (BMDM) |
-, 754327 |
3.4.21.B4 | granzyme K |
macrophage |
granzyme K is expressed and secreted by cultured classically activated macrophages |
754357 |
3.4.24.14 | procollagen N-endopeptidase |
macrophage |
- |
754590 |
3.4.24.34 | neutrophil collagenase |
macrophage |
- |
-, 754754 |
3.5.4.38 | single-stranded DNA cytosine deaminase |
macrophage |
- |
754831 |
3.4.24.B11 | ADAMTS1 endopeptidase |
macrophage |
macrophages at sites of muscle injury induce activation of satellite cells via expression of Adamts1 |
754846 |
3.4.22.57 | caspase-4 |
macrophage |
- |
754851 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
macrophage |
- |
755432 |
2.1.1.366 | [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase |
macrophage |
- |
755432 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
macrophage |
bone marrow-derived macrophages |
-, 756014 |
3.6.1.5 | apyrase |
macrophage |
- |
-, 756375 |
2.1.1.319 | type I protein arginine methyltransferase |
macrophage |
- |
756732 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
macrophage |
SIRT5 and SIRT1/2 have opposite expression patterns and functions in macrophages, overview |
757084 |
3.6.5.2 | small monomeric GTPase |
macrophage |
TLRs agonists induce changes in the expression of Rap2a in macrophages. In contrast to mRNA levels, Rap2a protein levels are increased after LPS treatments of macrophages |
757678 |
3.6.4.13 | RNA helicase |
macrophage |
- |
758198 |
2.6.1.42 | branched-chain-amino-acid transaminase |
macrophage |
- |
758657 |
2.3.2.25 | N-terminal E2 ubiquitin-conjugating enzyme |
macrophage |
- |
759122 |
2.4.1.274 | glucosylceramide beta-1,4-galactosyltransferase |
macrophage |
alveolar mactrophage |
759227 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
macrophage |
- |
760351 |
2.8.2.29 | [heparan sulfate]-glucosamine 3-sulfotransferase 2 |
macrophage |
primary macrophages. HS3ST2 is highly expressed in non-activated macrophages |
760623 |
2.8.2.30 | [heparan sulfate]-glucosamine 3-sulfotransferase 3 |
macrophage |
primary macrophages. HS3ST3B is highly expressed in activated macrophages, highest after alternative stimulation (M2 polarization), while the enzyme is not detected in proinflammatory macrophages (M1) |
760623 |
2.7.12.1 | dual-specificity kinase |
macrophage |
- |
761772 |
3.1.1.116 | sn-1-specific diacylglycerol lipase |
macrophage |
peritoneal macrophages |
761970 |
2.7.11.30 | receptor protein serine/threonine kinase |
macrophage |
- |
762408 |
1.3.1.21 | 7-dehydrocholesterol reductase |
macrophage |
- |
763129 |
1.2.1.104 | pyruvate dehydrogenase system |
macrophage |
- |
763502 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
macrophage |
- |
763502 |
1.14.13.9 | kynurenine 3-monooxygenase |
macrophage |
- |
763915, 764034 |
1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
macrophage |
highly expressed in immune-activated macrophages |
765804 |