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Information on EC 3.1.1.111 - phosphatidylserine sn-1 acylhydrolase

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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.1 Carboxylic-ester hydrolases
                3.1.1.111 phosphatidylserine sn-1 acylhydrolase
IUBMB Comments
The enzyme, which has been described from mammals, is specific for phosphatidylserine and 2-lysophosphatidylserine, and does not act on phosphatidylcholine, phosphatidylethanolamine, phosphatidic acid or phosphatidylinositol.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
a phosphatidylserine
+
=
a 2-acyl-1-lyso-phosphatidylserine
+
Synonyms
lipase member I, LIPI, phosphatidlyserine-specific phospholipase A1, phosphatidylserine-specific phospholipase A1, PLA1, PLA1A, PS-PLA1, PS-PLA1beta, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 1-acyl-2-lyso-phosphatidylserine + H2O = glycerophosphoserine + a fatty acid
show the reaction diagram
(2)
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-
-
a phosphatidylserine + H2O = a 2-acyl-1-lyso-phosphatidylserine + a fatty acid
show the reaction diagram
(1)
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-
-
PATHWAY SOURCE
PATHWAYS
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